Endovascular versus medical management of atherosclerotic renovascular disease: update and emerging concepts

M Pappaccogli, T Robberechts, JP Lengelé… - …, 2023 - Am Heart Assoc
Atherosclerotic renovascular disease is the most frequent cause of renovascular
hypertension and its prevalence increases with age and in specific subset of patients, such …

Targeting CD 36‐Mediated Inflammation Reduces Acute Brain Injury in Transient, but not Permanent, Ischemic Stroke

EH Kim, AT Tolhurst, HH Szeto… - CNS neuroscience & …, 2015 - Wiley Online Library
Aims The pathology of stroke consists of multiple pro‐death processes, and CD 36 has been
suggested as a multimodal target to reduce oxidative stress and inflammation in ischemic …

Intrarenal delivery of mesenchymal stem cells and endothelial progenitor cells attenuates hypertensive cardiomyopathy in experimental renovascular hypertension

A Eirin, XY Zhu, B Ebrahimi, JD Krier… - Cell …, 2015 - journals.sagepub.com
Renovascular hypertension (RVH) leads to left ventricular (LV) hypertrophy and diastolic
dysfunction, associated with increased cardiovascular mortality. Intrarenal delivery of …

Renal vein cytokine release as an index of renal parenchymal inflammation in chronic experimental renal artery stenosis

A Eirin, X Zhang, XY Zhu, H Tang… - Nephrology Dialysis …, 2014 - academic.oup.com
Background Renal parenchymal inflammation is a critical determinant of kidney injury in
renal artery stenosis (RAS) but is difficult to assess in the single kidney without tissue …

Mitochondrial dysfunction contributes to hypertensive target organ damage: lessons from an animal model of human disease

S Rubattu, R Stanzione, M Volpe - Oxidative medicine and …, 2016 - Wiley Online Library
Mechanisms underlying hypertensive target organ damage (TOD) are not completely
understood. The pathophysiological role of mitochondrial oxidative stress, resulting from …

Hydrogen sulfide inhibits Ca2+-induced mitochondrial permeability transition pore opening in type-1 diabetes

AS Papu John, S Kundu… - American Journal …, 2019 - journals.physiology.org
Hydrogen sulfide (H2S) attenuates N-methyl-d-aspartate receptor-R1 (NMDA-R1) and
mitigates diabetic renal damage; however, the molecular mechanism is not well known …

Intra-renal delivery of mesenchymal stem cells attenuates myocardial injury after reversal of hypertension in porcine renovascular disease

A Eirin, XY Zhu, CM Ferguson, SM Riester… - Stem cell research & …, 2015 - Springer
Introduction Percutaneous transluminal renal angioplasty (PTRA) fails to fully improve
cardiac injury and dysfunction in patients with renovascular hypertension (RVH) …

Renovascular disease induces mitochondrial damage in swine scattered tubular cells

AA Nargesi, XY Zhu, SM Conley… - American Journal …, 2019 - journals.physiology.org
Scattered tubular-like cells (STCs) contribute to repair neighboring injured renal tubular
cells. Mitochondria mediate STC biology and function but might be injured by the ambient …

Mesenchymal stem/stromal cell-derived extracellular vesicles elicit better preservation of the intra-renal microvasculature than renal revascularization in pigs with …

CM Ferguson, RA Farahani, XY Zhu, H Tang… - Cells, 2021 - mdpi.com
Background: Percutaneous transluminal renal angioplasty (PTRA) confers clinical and
mortality benefits in select 'high-risk'patients with renovascular disease (RVD). Intra-renal …

Stealth peptides target cellular powerhouses to fight rare and common age-related diseases

HH Szeto - Protein and Peptide Letters, 2018 - ingentaconnect.com
Background: Mitochondria are the primary source of energy in most tissues. Mitochondrial
dysfunction results in cellular energy deficiency, triggers the production of reactive oxygen …