The role of hypoxia in ischemic chronic kidney disease

SC Textor, LO Lerman - Seminars in nephrology, 2019 - Elsevier
A gradually developing reduction in renal blood flow from atherosclerotic renovascular
disease results in loss of kidney volume and a decrease in glomerular filtration rate that …

New drugs for acute kidney injury

JM Côté, PT Murray, MH Rosner - Current Opinion in Critical Care, 2020 - journals.lww.com
New drugs for acute kidney injury : Current Opinion in Critical Care New drugs for acute kidney
injury : Current Opinion in Critical Care Log in or Register Subscribe to journalSubscribe Get …

Metabolic Syndrome Alters the Cargo of Mitochondria‐Related microRNAs in Swine Mesenchymal Stem Cell‐Derived Extracellular Vesicles, Impairing Their Capacity …

RA Farahani, XY Zhu, H Tang, KL Jordan… - Stem Cells …, 2020 - Wiley Online Library
Background. Coexisting metabolic syndrome (MetS) and renal artery stenosis (RAS) are
linked to poor renal outcomes. Mesenchymal stem/stromal cell‐(MSC‐) derived extracellular …

Emerging paradigms in chronic kidney ischemia

A Eirin, SC Textor, LO Lerman - Hypertension, 2018 - Am Heart Assoc
1024 Hypertension November 2018 to be overly simplistic and has a limited relationship to
the severity of functional impairment. As a result, recruitment and enrollment of patients for …

Mitochondrial targeted peptides preserve mitochondrial organization and decrease reversible myocardial changes in early swine metabolic syndrome

F Yuan, JR Woollard, KL Jordan… - Cardiovascular …, 2018 - academic.oup.com
Aims The mechanisms responsible for cardiac damage in the early stages of metabolic
syndrome (MetS) remain unknown. Mitochondria are intimately associated with cellular …

Methods and compositions for preventing or treating ophthalmic conditions

L Liu, S Tang, X Liang - US Patent 9,023,807, 2015 - Google Patents
US9023807B2 - Methods and compositions for preventing or treating ophthalmic conditions
- Google Patents US9023807B2 - Methods and compositions for preventing or treating …

Recent advances in the pharmacological management of sepsis-associated acute kidney injury

K Kalantari, MH Rosner - Expert Review of Clinical Pharmacology, 2021 - Taylor & Francis
Introduction Acute kidney injury is a common occurrence in patients with sepsis and
portends a high mortality as well as increased morbidity with numerous sequelae including …

Renal artery stenosis: if and when to intervene

SC Textor, MM McKusick - Current opinion in nephrology and …, 2016 - journals.lww.com
Clinicians must recognize clinical syndromes that identify 'high-risk'groups and apply
revascularization in those likely to benefit. Future efforts to protect the kidney (eg …

Peripheral vascular atherosclerosis in a novel PCSK9 gain-of-function mutant Ossabaw miniature pig model

AF Hedayat, KH Park, TG Kwon, JR Woollard… - Translational …, 2018 - Elsevier
Hypercholesterolemia is a major risk factor for atherosclerosis. Remaining challenges in the
management of atherosclerosis necessitate development of animal models that mimic …

Mitochondrial dysfunction in the pathophysiology of renal diseases

Y Guo, R Che, P Wang… - American Journal of …, 2024 - journals.physiology.org
Mitochondria are essential organelles in the human body, serving as the metabolic factory of
the whole organism. When mitochondria are dysfunctional, it can affect all organs of the …