Chronic renal ischemia in humans: can cell therapy repair the kidney in occlusive renovascular disease?

A Saad, SM Herrmann, SC Textor - Physiology, 2015 - journals.physiology.org
Occlusive renovascular disease caused by atherosclerotic renal artery stenosis (ARAS)
elicits complex biological responses that eventually lead to loss of kidney function. Recent …

Antitumor effect and toxicity of an albumin-paclitaxel nanocarrier system constructed via controllable alkali-induced conformational changes

G Gong, Y Jiao, Q Pan, H Tang, Y An… - ACS Biomaterials …, 2019 - ACS Publications
Various strategies have been developed to construct albumin nanomaterials via biophysical
or chemical changes. In this work, a compound comprising albumin-paclitaxel nanoparticles …

[HTML][HTML] Experimental coronary artery stenosis accelerates kidney damage in renovascular hypertensive swine

D Sun, A Eirin, XY Zhu, X Zhang, JA Crane… - Kidney international, 2015 - Elsevier
The impact of coronary artery stenosis (CAS) on renal injury is unknown. Here we tested
whether the existence of CAS, regardless of concurrent atherosclerosis, would induce …

Atherosclerotic renal artery stenosis in the post-CORAL era part 2: new directions in transcatheter nephron salvage following flawed revascularization trials

AA Sag, TA Sos, C Benli, O Sal, P Rossignol… - Journal of the American …, 2016 - Elsevier
Unlike endovascular therapeutic studies for atherosclerosis in many other vascular beds,
major trials regarding endovascular renovascular revascularization have resulted in a …

Renovascular hypertension: is there still a role for stent revascularization?

SC Textor - Current opinion in nephrology and hypertension, 2013 - journals.lww.com
Renovascular hypertension: is there still a role for stent r... : Current Opinion in Nephrology and
Hypertension Renovascular hypertension: is there still a role for stent revascularization …

Mitochondrial protective agents for ischemia/reperfusion injury

RA Kloner - Circulation: Cardiovascular Interventions, 2017 - Am Heart Assoc
2 Kloner Mitochondrial Protective Agents had no beneficial effects on either infarct size or no
reflow. The end points of this clinical trial included myocardial infarct size as assessed by …

Role of 2′, 3′-cyclic nucleotide 3′-phosphodiesterase in the renal 2′, 3′-cAMP-adenosine pathway

EK Jackson, DG Gillespie, Z Mi… - American Journal …, 2014 - journals.physiology.org
Energy depletion increases the renal production of 2′, 3′-cAMP (a positional isomer of
3′, 5′-cAMP that opens mitochondrial permeability transition pores) and 2′, 3′-cAMP is …

Novel therapeutic strategies for renovascular disease

A Eirin, SC Textor, LO Lerman - Current opinion in nephrology …, 2019 - journals.lww.com
Experimental studies and pilot clinical trials suggest that therapies targeting renal
inflammation, microvascular remodeling, and mitochondrial damage have the potential to …

Percutaneous transluminal renal angioplasty attenuates poststenotic kidney mitochondrial damage in pigs with renal artery stenosis and metabolic syndrome

RA Farahani, M Afarideh, XY Zhu… - Journal of cellular …, 2021 - Wiley Online Library
Percutaneous transluminal renal angioplasty (PTRA) has been used to treat renovascular
disease (RVD), a chronic condition characterized by renal ischemia and metabolic …

Methods for preventing or treating mitochondrial permeability transition

HH Szeto, PW Schiller, K Zhao - US Patent 8,957,030, 2015 - Google Patents
Related US Application Data Continuation of application No. 13/247,648, filed on Sep. 28,
2011, now Pat. No. 8,404,646, which is a continuation of application No. 12/753,403, filed on …