The pivotal role of the placenta in normal and pathological pregnancies: a focus on preeclampsia, fetal growth restriction, and maternal chronic venous disease
MA Ortega, O Fraile-Martínez, C García-Montero… - Cells, 2022 - mdpi.com
The placenta is a central structure in pregnancy and has pleiotropic functions. This organ
grows incredibly rapidly during this period, acting as a mastermind behind different fetal and …
grows incredibly rapidly during this period, acting as a mastermind behind different fetal and …
Pathogenesis, diagnosis and management of obstetric antiphospholipid syndrome: a comprehensive review
J Alijotas-Reig, E Esteve-Valverde… - Journal of clinical …, 2022 - mdpi.com
Antiphospholipid syndrome is an autoimmune disorder characterized by vascular
thrombosis and/or pregnancy morbidity associated with persistent antiphospholipid antibody …
thrombosis and/or pregnancy morbidity associated with persistent antiphospholipid antibody …
Cardiovascular risk factors mediate the long-term maternal risk associated with hypertensive disorders of pregnancy
Background Hypertensive disorders of pregnancy (HDP), including gestational hypertension
and preeclampsia, are associated with an increased risk of CVD. Objectives The purpose of …
and preeclampsia, are associated with an increased risk of CVD. Objectives The purpose of …
Polygenic prediction of preeclampsia and gestational hypertension
Preeclampsia and gestational hypertension are common pregnancy complications
associated with adverse maternal and child outcomes. Current tools for prediction …
associated with adverse maternal and child outcomes. Current tools for prediction …
CCL2: An important cytokine in normal and pathological pregnancies: A review
Z Lin, JL Shi, M Chen, ZM Zheng, MQ Li… - Frontiers in …, 2023 - frontiersin.org
CC motif ligand 2 (CCL2), also known as monocytic chemotactic protein 1 (MCP-1), is an
integral chemotactic factor which recruits macrophages for the immune response. Together …
integral chemotactic factor which recruits macrophages for the immune response. Together …
Iron metabolism and ferroptosis in physiological and pathological pregnancy
Y Zhang, Y Lu, L Jin - International Journal of Molecular Sciences, 2022 - mdpi.com
Iron is a vital element in nearly every living organism. During pregnancy, optimal iron
concentration is essential for both maternal health and fetal development. As the barrier …
concentration is essential for both maternal health and fetal development. As the barrier …
Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome‐Induced Pyroptosis via Inhibiting the TLR4/NF‐κB/PFKFB3 Signaling in …
Y Zhang, W Liu, Y Zhong, Q Li, M Wu… - Oxidative Medicine …, 2021 - Wiley Online Library
NOD‐like receptor family, pyrin domain‐containing protein 3 (NLRP3) inflammasome‐
mediated pyroptosis is a crucial event in the preeclamptic pathogenesis, tightly linked with …
mediated pyroptosis is a crucial event in the preeclamptic pathogenesis, tightly linked with …
Pathophysiology and risk factors of peripartum cardiomyopathy
Peripartum cardiomyopathy (PPCM) is a potentially fatal form of idiopathic heart failure with
variable prevalence across different countries and ethnic groups. The cause of PPCM is …
variable prevalence across different countries and ethnic groups. The cause of PPCM is …
NLRP3 activation and its relationship to endothelial dysfunction and oxidative stress: implications for preeclampsia and pharmacological interventions
Preeclampsia (PE) is a specific syndrome of human pregnancy, being one of the main
causes of maternal death. Persistent inflammation in the endothelium stimulates the …
causes of maternal death. Persistent inflammation in the endothelium stimulates the …
The role of peroxisome proliferator-activated receptors in preeclampsia
I Psilopatis, K Vrettou, FN Fleckenstein, S Theocharis - Cells, 2023 - mdpi.com
Preeclampsia is a common pregnancy-related hypertensive disorder. Often presenting as
preexisting or new-onset hypertension complicated by proteinuria and/or end-organ …
preexisting or new-onset hypertension complicated by proteinuria and/or end-organ …