miRNAs and apoptosis: RNAs to die for
M Jovanovic, MO Hengartner - Oncogene, 2006 - nature.com
MicroRNAs (miRNAs) are small non-coding RNAs of about 18–24 nucleotides in length that
negatively regulate gene expression. Discovered only recently, it has become clear that they …
negatively regulate gene expression. Discovered only recently, it has become clear that they …
Lost in translation: an assessment and perspective for computational microRNA target identification
P Alexiou, M Maragkakis, GL Papadopoulos… - …, 2009 - academic.oup.com
MicroRNAs (miRNAs) are a class of short endogenously expressed RNA molecules that
regulate gene expression by binding directly to the messenger RNA of protein coding …
regulate gene expression by binding directly to the messenger RNA of protein coding …
miR-34a repression of SIRT1 regulates apoptosis
M Yamakuchi, M Ferlito… - Proceedings of the …, 2008 - National Acad Sciences
MicroRNA 34a (miR-34a) is a tumor suppressor gene, but how it regulates cell proliferation
is not completely understood. We now show that the microRNA miR-34a regulates silent …
is not completely understood. We now show that the microRNA miR-34a regulates silent …
[HTML][HTML] Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha
The signal transducers of the transforming growth factor β (TGFβ)/bone morphogenetic
protein (BMP), the Smads, promote the expression of a subset of miRNAs by facilitating the …
protein (BMP), the Smads, promote the expression of a subset of miRNAs by facilitating the …
The role of microRNAs in cancer: no small matter
EAC Wiemer - European journal of cancer, 2007 - Elsevier
MicroRNAs are a recently discovered class of small, evolutionarily conserved, RNA
molecules that negatively regulate gene expression at the post-transcriptional level. Mature …
molecules that negatively regulate gene expression at the post-transcriptional level. Mature …
Energizing miRNA research: a review of the role of miRNAs in lipid metabolism, with a prediction that miR-103/107 regulates human metabolic pathways
MicroRNAs (miRNAs) are powerful regulators of gene expression. Although first discovered
in worm larvae, miRNAs play fundamental biological roles—including in humans—well …
in worm larvae, miRNAs play fundamental biological roles—including in humans—well …
Implications of micro-RNA profiling for cancer diagnosis
JM Cummins, VE Velculescu - Oncogene, 2006 - nature.com
Micro-RNAs (miRNAs) are a large class of small non-coding RNAs that regulate protein
expression in eucaryotic cells. Initially believed to be unique to the nematode …
expression in eucaryotic cells. Initially believed to be unique to the nematode …
MicroRNAs and chromosomal abnormalities in cancer cells
Over the past five decades, a plethora of nonrandom chromosomal abnormalities have been
consistently reported in malignant cells facilitating the identification of cancer-associated …
consistently reported in malignant cells facilitating the identification of cancer-associated …
Epigenetic silencing of MicroRNA miR-107 regulates cyclin-dependent kinase 6 expression in pancreatic cancer
KH Lee, C Lotterman, C Karikari, N Omura… - Pancreatology, 2009 - Elsevier
Aberrant expression of microRNAs (miRNAs) has emerged as an important hallmark of
cancer. However, the putative mechanisms regulating miRNAs per se are only partially …
cancer. However, the putative mechanisms regulating miRNAs per se are only partially …
The role of miR-128 in cancer development, prevention, drug resistance, and immunotherapy
A growing body of evidence has revealed that microRNA (miRNA) expression is
dysregulated in cancer, and they can act as either oncogenes or suppressors under certain …
dysregulated in cancer, and they can act as either oncogenes or suppressors under certain …