Considering the complexity of the current framework in oncology, the relevance of animal
models in biomedical research is critical in light of the capacity to produce valuable data with …

Though relatively rare in dogs, prostate cancer (PCa) is the most common non‐cutaneous
cancer in men. Human and canine prostate glands share many functional, anatomical and …

Prostate cancer (PCa) in dogs is a highly malignant disease akin to its human counterpart. In
contrast to the situation in humans, multi-gene approaches facilitating risk stratification of …

Background Male dogs can develop spontaneous prostate cancer, which is similar
physiologically to human disease. Recently, Tweedle and coworkers have developed an …

Canine prostate adenocarcinoma (PAC) and transitional cell carcinoma (TCC) of prostate
and urinary bladder are highly invasive and metastatic tumors of closely neighbored organs …

Shear wave elastography (SWE) induces lateral shear wave through acoustic pulses of the
transducer and evaluates tissue stiffness quantitatively. This study was performed to …

Preclinical studies in rodent models have been a pivotal role in human clinical research, but
many of them fail in the translational process. Spontaneous tumors in pet dogs have the …

Chimeric antigen receptors (CARs) recently gained momentum in cancer treatment due to
their ability to promote T‑cell mediated responses to a specific tumor‑associated antigen …

Claudin (CLDN) proteins are commonly expressed in cancers and targeted in novel
therapeutic approaches. The C-terminal of Clostridium perfringens enterotoxin (C-CPE) …

Background: When trying to modify urinary stents, certain pre-clinical steps have to be
followed before clinical evaluation in humans. Usually, the process starts as an in silico …