Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications
S Hong, WA Banks - Brain, behavior, and immunity, 2015 - Elsevier
Individuals living with HIV who are optimally treated with combination antiretroviral therapy
(cART) can now lead an extended life. In spite of this remarkable survival benefit from viral …
(cART) can now lead an extended life. In spite of this remarkable survival benefit from viral …
[HTML][HTML] Microglial pathology
WJ Streit, QS Xue, J Tischer, I Bechmann - Acta neuropathologica …, 2014 - Springer
This paper summarizes pathological changes that affect microglial cells in the human brain
during aging and in aging-related neurodegenerative diseases, primarily Alzheimer's …
during aging and in aging-related neurodegenerative diseases, primarily Alzheimer's …
Validity of the CogState brief battery: relationship to standardized tests and sensitivity to cognitive impairment in mild traumatic brain injury, schizophrenia, and AIDS …
This study examined the validity of the four standard psychological paradigms that have
been operationally defined within the CogState brief computerized cognitive assessment …
been operationally defined within the CogState brief computerized cognitive assessment …
Human immunodeficiency virus‐associated neurocognitive disorders: mind the gap
JC McArthur, J Steiner, N Sacktor, A Nath - Annals of neurology, 2010 - Wiley Online Library
Human immunodeficiency virus (HIV)‐associated neurocognitive disorders (HANDs) remain
among the most common disorders in people infected with HIV, even in an era when potent …
among the most common disorders in people infected with HIV, even in an era when potent …
[HTML][HTML] Macrophages and their relevance in Human Immunodeficiency Virus Type I infection
H Koppensteiner, R Brack-Werner, M Schindler - Retrovirology, 2012 - Springer
Macrophages are important target cells for the Human Immunodeficiency Virus Type I (HIV-
1) in vivo. Several studies have assessed the molecular biology of the virus in this cell type …
1) in vivo. Several studies have assessed the molecular biology of the virus in this cell type …
Current understanding of HIV-associated neurocognitive disorders pathogenesis
P Gannon, MZ Khan, DL Kolson - Current opinion in neurology, 2011 - journals.lww.com
Prevention and treatment of HAND requires strategies aimed at suppressing CNS HIV
replication and effects of systemic and CNS inflammation in aging and substance-abusing …
replication and effects of systemic and CNS inflammation in aging and substance-abusing …
Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection
Objective: Mild forms of HIV-associated neurocognitive disorders (HAND) remain prevalent
in the era of combination antiretroviral therapy (cART). Although elevated …
in the era of combination antiretroviral therapy (cART). Although elevated …
Monocyte maturation, HIV susceptibility, and transmigration across the blood brain barrier are critical in HIV neuropathogenesis
DW Williams, EA Eugenin, TM Calderon… - Journal of leukocyte …, 2012 - academic.oup.com
ABSTRACT HIV continues to be a global health crisis with more than 34 million people
infected worldwide (UNAIDS: Report on the Global AIDS Epidemic 2010, Geneva, World …
infected worldwide (UNAIDS: Report on the Global AIDS Epidemic 2010, Geneva, World …
[HTML][HTML] Brain cell reservoirs of latent virus in presymptomatic HIV-infected individuals
KA Thompson, CL Cherry, JE Bell… - The American journal of …, 2011 - Elsevier
We detected HIV-1 DNA in pure populations of perivascular macrophages, parenchymal
microglia, and astrocytes, isolated using laser microdissection from brain tissue of five …
microglia, and astrocytes, isolated using laser microdissection from brain tissue of five …
Cliniconeuropathologic correlates of human immunodeficiency virus in the era of antiretroviral therapy
I Everall, F Vaida, N Khanlou, D Lazzaretto… - Journal of …, 2009 - Springer
The objective of this study was to examine the spectrum of human immunodeficiency virus
(HIV) brain pathology and its clinical correlates in the antiretroviral era. We carried out a …
(HIV) brain pathology and its clinical correlates in the antiretroviral era. We carried out a …