Bioorthogonal chemistry reactions occur in physiological conditions without interfering with
normal physiological processes. Through metabolic engineering, bioorthogonal groups can …

The COVID-19 pandemic highlights the need for diagnostics that can be rapidly adapted
and deployed in a variety of settings. Several SARS-CoV-2 variants have shown worrisome …

The fast-developing synthetic biology (SB) has provided many genetic tools to reprogram
and engineer cells for improved performance, novel functions, and diverse applications …

Nucleic acid sensing powered by the sequence recognition of CRIPSR technologies has
enabled major advancement toward rapid, accurate and deployable diagnostics. While …

In low-resource settings, resilience to infectious disease outbreaks can be hindered by
limited access to diagnostic tests. Here we report the results of double-blinded studies of the …

We report here the development of an electrochemical cell‐free biosensor for antibody
detection directly in complex sample matrices with high sensitivity and specificity that is …

Huntington's disease is an autosomal-dominant neurodegenerative disease caused by CAG
expansion in exon 1 of the huntingtin (HTT) gene. Since mutant huntingtin (mHTT) protein is …

We report here the development of a cell-free in vitro transcription system for the detection of
specific target antibodies. The approach is based on the use of programmable antigen …

Traceless physical cues are desirable for remote control of the in situ production and real-
time dosing of biopharmaceuticals in cell-based therapies. However, current optogenetic …

Materials in nature have fascinating properties that serve as a continuous source of
inspiration for materials scientists. Accordingly, bio-mimetic and bio-inspired approaches …