Harnessing synthetic biology for advancing RNA therapeutics and vaccine design

BA Pfeifer, M Beitelshees, A Hill, J Bassett… - NPJ Systems Biology …, 2023 - nature.com
Recent global events have drawn into focus the diversity of options for combatting disease
across a spectrum of prophylactic and therapeutic approaches. The recent success of the …

[HTML][HTML] Multifaceted Applications of Synthetic Microbial Communities: Advances in Biomedicine, Bioremediation, and Industry

EA Contreras-Salgado, AG Sánchez-Morán… - Microbiology …, 2024 - mdpi.com
The broad range of applications offered by synthetic biology and bioengineering has
revolutionized the ability to design and redesign microorganisms to express specific …

Evaluation of human performance aiding live synthetically engineered bacteria in a gut-on-a-chip

MT Nelson, HG Coia, C Holt… - ACS Biomaterials …, 2022 - ACS Publications
Synbiotics are a new class of live therapeutics employing engineered genetic circuits. The
rapid adoption of genetic editing tools has catalyzed the expansion of possible synbiotics …

Current advances of biocontainment strategy in synthetic biology

X Zhu, Z Zhang, B Jia, Y Yuan - Chinese Journal of Chemical Engineering, 2023 - Elsevier
Synthetic biotechnology has led to the widespread application of genetically modified
organisms (GMOs) in biochemistry, bioenergy, and therapy. However, the uncontrolled …

Engineering biology and climate change mitigation: Policy considerations

J Symons, TA Dixon, J Dalziell, N Curach… - Nature …, 2024 - nature.com
Engineering biology (EngBio) is a dynamic field that uses gene editing, synthesis, assembly,
and engineering to design new or modified biological systems. EngBio applications could …

A review of synthetic biology tools in Yarrowia lipolytica

L Cao, J Li, Z Yang, X Hu, P Wang - World Journal of Microbiology and …, 2023 - Springer
Yarrowia lipolytica is a non-conventional oleaginous yeast with great potential for industrial
production. Y. lipolytica has a high propensity for flux through tricarboxylic acid cycle …

[HTML][HTML] Synthetic biology in Indonesia: Potential and projection in a country with mega biodiversity

I Sanka, AB Kusuma, F Martha, A Hendrawan… - Biotechnology …, 2023 - Elsevier
Synthetic biology has gained many interest around the globe in the last two decades, not
only due to its rapid development but also the potential to provide addressable solutions …

[HTML][HTML] Advancing pathogen detection for airborne diseases

T Zhai, Y Wei, L Wang, J Li, C Fan - Fundamental Research, 2023 - Elsevier
Airborne diseases including SARS, bird flu, and the ongoing Coronavirus Disease 2019
(COVID-19) have stimulated the demand for developing novel bioassay methods competent …

Optimization of CRISPR–Cas system for clinical cancer therapy

X Meng, T Wu, Q Lou, K Niu, L Jiang… - Bioengineering & …, 2023 - Wiley Online Library
Cancer is a genetic disease caused by alterations in genome and epigenome and is one of
the leading causes for death worldwide. The exploration of disease development and …

合成生物学助力细菌疫苗研发

章金勇, 顾江, 关山, 李海波, 曾浩, 邹全明 - 合成生物学, 2024 - synbioj.cip.com.cn
细菌感染已成为全球第二大死亡因素, 给人类健康与公共安全造成了巨大威胁.
抗生素一直是治疗细菌感染最为主要的手段, 但越来越严重的耐药问题给传统的抗生素疗法带来 …