Targeting TRPV1 for Cancer Pain Relief: Can It Work?

A Szallasi - Cancers, 2024 - mdpi.com
Simple Summary Medical control of cancer pain is often unsatisfactory. Narcotic drugs
(opioids) are effective pain killers, but they have important negative effects on the central …

Intercellular pathways of cancer treatment-related cardiotoxicity and their therapeutic implications: The paradigm of radiotherapy

S Logotheti, A Pavlopoulou, HK Rudsari… - Pharmacology & …, 2024 - Elsevier
Advances in cancer therapeutics have improved patient survival rates. However, cancer
survivors may suffer from adverse events either at the time of therapy or later in life …

Nerve terminals in the tumor microenvironment as targets for local infiltration analgesia

P Madhusudanan, C Jerard, G Raju, N Katiyar… - Neuroscience …, 2023 - Elsevier
Nerve terminals within the tumor microenvironment as potential pain-mitigating targets for
local infiltration analgesia is relatively less explored. In this study, we examine the role of key …

Modulation of host immunity by sensory neurons

T Saraiva-Santos, TH Zaninelli, FA Pinho-Ribeiro - Trends in Immunology, 2024 - cell.com
Recent studies have uncovered a new role for sensory neurons in influencing mammalian
host immunity, challenging conventional notions of the nervous and immune systems as …