High-resolution two-photon polymerization: The most versatile technique for the fabrication of microneedle arrays

Z Faraji Rad, PD Prewett, GJ Davies - Microsystems & nanoengineering, 2021 - nature.com
Microneedle patches have received much interest in the last two decades as drug/vaccine
delivery or fluid sampling systems for diagnostic and monitoring purposes. Microneedles are …

Engineering microneedle patches for improved penetration: analysis, skin models and factors affecting needle insertion

P Makvandi, M Kirkby, ARJ Hutton, M Shabani… - Nano-Micro Letters, 2021 - Springer
Transdermal microneedle (MN) patches are a promising tool used to transport a wide variety
of active compounds into the skin. To serve as a substitute for common hypodermic needles …

Microneedle array systems for long-acting drug delivery

LK Vora, K Moffatt, IA Tekko, AJ Paredes… - European Journal of …, 2021 - Elsevier
The development of microneedles (MNs) assisted drug delivery technologies have been
highly active for more than two decades. The minimally invasive and self-administered MN …

The role of 3D printing technology in microengineering of microneedles

U Detamornrat, E McAlister, ARJ Hutton, E Larrañeta… - Small, 2022 - Wiley Online Library
Microneedles (MNs) are minimally invasive devices, which have gained extensive interest
over the past decades in various fields including drug delivery, disease diagnosis …

Polymeric microneedle-mediated transdermal delivery of melittin for rheumatoid arthritis treatment

G Du, P He, J Zhao, C He, M Jiang, Z Zhang… - Journal of Controlled …, 2021 - Elsevier
Transdermal drug delivery systems for rheumatoid arthritis (RA) have been receiving
increasing attention as they can potentially overcome drawbacks which exist in traditional …

[HTML][HTML] Advancements, challenges and future perspectives on peptide-based drugs: Focus on antimicrobial peptides

X Luo, H Chen, Y Song, Z Qin, L Xu, N He, Y Tan… - European Journal of …, 2023 - Elsevier
Among other health related issues, the rising concerns on drug resistance led to look for
alternative pharmaceutical drugs that are effective both against infectious and noninfectious …

[HTML][HTML] Design and fabrication of customizable microneedles enabled by 3D printing for biomedical applications

JM Loh, YJL Lim, JT Tay, HM Cheng, HL Tey, K Liang - Bioactive Materials, 2024 - Elsevier
Microneedles (MNs) is an emerging technology that employs needles ranging from 10 to
1000 μm in height, as a minimally invasive technique for various procedures such as …

Microneedle-mediated transdermal delivery of biopharmaceuticals

HX Nguyen, CN Nguyen - Pharmaceutics, 2023 - mdpi.com
Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …

Microneedles for gene and drug delivery in skin cancer therapy

D Zhi, T Yang, T Zhang, M Yang, S Zhang… - Journal of Controlled …, 2021 - Elsevier
The success of skin cancer treatment is severely limited in the route of administration
because most genes and drugs cannot break through the excellent stratum corneum (SC) …

Microneedle-based insulin transdermal delivery system: current status and translation challenges

J Zhao, G Xu, X Yao, H Zhou, B Lyu, S Pei… - Drug Delivery and …, 2022 - Springer
Diabetes mellitus is a metabolic disease manifested by hyperglycemia. For patients with
type 1 and advanced type 2 diabetes mellitus, insulin therapy is essential. Subcutaneous …