Background Despite the evidence of declining sperm counts worldwide and the increasing
prevalence of male infertility, there has been limited documentation of the potential causes …

Infertility affects about 7% of all men. The etiology of impaired sperm production and function
can be related to factors acting at pre-testicular, post-testicular or directly at the testicular …

Background Spermatozoa morphology is an important and complex characteristic of the
fertilization capacity of male germ cells. Morphological abnormalities have been observed to …

BACKGROUND In spite of tremendous efforts by a number of groups, the search for single
nucleotide polymorphisms (SNPs) strongly associated with male factor infertility by means of …

Despite the identification of an increasing number of candidate genes involved in
spermatogenesis, the armamentarium of diagnostic genetic tests in male infertility remains …

Deletions involving the Y chromosome's AZFc region are the most common known genetic
cause of severe spermatogenic failure (SSF). Six recurrent interstitial deletions affecting the …

The spermatozoon is an accessible cell which can be easily purified and therefore it is
particularly well suited for proteomic analysis. It is also an extremely differentiated cell with …

Spermatozoa deliver more than the paternal genome into the oocyte; they also carry
remnant messenger RNA from spermatogenesis. The RNA profiles of spermatozoa from …

Objective To determine whether microRNA (miRNA) expression profile is different in
extracellular microvesicles collected from seminal plasma of men with …

The role of partial AZFc deletions of the Y chromosome in spermatogenic impairment is
currently debated. Recently, it was also reported that duplications of the same region are …