Autonomic dysfunction and chronic inflammation contribute to the pathogenesis and
progression of several cardiovascular diseases (CVD), such as heart failure with preserved …

Altered autonomic balance is a hallmark of numerous cardiovascular diseases, including
myocardial infarction (MI). Although device-based vagal stimulation is cardioprotective …

Purpose of review This review aims to provide an overview of the neural innervation of the
cardiovascular system and present a summary of current autonomic targets for a variety of …

Myocardial infarction (MI) stands as the predominant cause of morbidity and mortality within
the spectrum of cardiovascular diseases, with an unfavorable long-term prognosis. Vagus …

Cardiac disease progression reflects the dynamic interaction between adversely remodeled
neurohumoral control systems and an abnormal cardiac substrate. Vagal nerve stimulation …

The autonomic nervous system regulates all aspects of cardiac function including
chronotropy, inotropy, dromotropy, and lusitropy. 1 Furthermore, autonomic dysregulation …

Intrinsic cardiac neurons (ICNs) play a crucial role in the proper functioning of the heart; yet
a paucity of data pertaining to human ICNs exists. We took a multidisciplinary approach to …

Cardiovascular disease is the most common cause of death worldwide, resulting in millions
of deaths annually. Currently, there are still some deficiencies in the treatment of …

—Benjamin Franklin 1 As perfectly depicted by Franklin's famous quote, time is of the
essence when dealing with acute myocardial ischemia, and the concept that “time is muscle” …

Abstract Background and Objectives: Spatially-selective vagus nerve stimulation (sVNS)
offers a promising solution to mitigate the off-target effects associated with traditional VNS …