Tobacco smoke carcinogens and lung cancer

SS Hecht - Journal of the national cancer institute, 1999 - academic.oup.com
The complexity of tobacco smoke leads to some confusion about the mechanisms by which
it causes lung cancer. Among the multiple components of tobacco smoke, 20 carcinogens …

Tobacco carcinogens, their biomarkers and tobacco-induced cancer

SS Hecht - Nature Reviews Cancer, 2003 - nature.com
The devastating link between tobacco products and human cancers results from a powerful
alliance of two factors—nicotine and carcinogens. Without either one of these, tobacco …

Tobacco smoking and cancer: a meta‐analysis

S Gandini, E Botteri, S Iodice, M Boniol… - … journal of cancer, 2008 - Wiley Online Library
We conducted a systematic meta‐analysis of observational studies on cigarette smoking
and cancer from 1961 to 2003. The aim was to quantify the risk for 13 cancer sites …

Assessing secondhand smoke using biological markers

E Avila-Tang, WK Al-Delaimy, DL Ashley… - Tobacco …, 2013 - tobaccocontrol.bmj.com
Secondhand smoke exposure (SHSe) is a known cause of many adverse health effects in
adults and children. Increasingly, SHSe assessment is an element of tobacco control …

Clearing the smoke: assessing the science base for tobacco harm reduction

S Bondurant, R Wallace, P Shetty, K Stratton - 2001 - books.google.com
Despite overwhelming evidence of tobacco's harmful effects and pressure from anti-smoking
advocates, current surveys show that about one-quarter of all adults in the United States are …

Human urinary carcinogen metabolites: biomarkers for investigating tobacco and cancer

SS Hecht - Carcinogenesis, 2002 - academic.oup.com
Measurement of human urinary carcinogen metabolites is a practical approach for obtaining
important information about tobacco and cancer. This review presents currently available …

Identifying health disparities across the tobacco continuum

P Fagan, ET Moolchan, D Lawrence, A Fernander… - …, 2007 - Wiley Online Library
Aims Few frameworks have addressed work‐force diversity, inequities and inequalities as
part of a comprehensive approach to eliminating tobacco‐related health disparities. This …

Tobacco use and cancer: an epidemiologic perspective for geneticists

MJ Thun, SJ Henley, EE Calle - Oncogene, 2002 - nature.com
Much of what is known about the deleterious effects of tobacco use on health was learned
from epidemiologic studies over the last half century. These studies establish unequivocally …

Epidemiology of menthol cigarette use

GA Giovino, S Sidney, JC Gfroerer… - Nicotine & Tobacco …, 2004 - academic.oup.com
Approximately one-fourth of all cigarettes sold in the United States are mentholated. An
understanding of the consequences, patterns, and correlates of menthol cigarette use can …

Ethnic differences in N-glucuronidation of nicotine and cotinine

NL Benowitz, EJ Perez-Stable, I Fong, G Modin… - … of Pharmacology and …, 1999 - ASPET
We previously reported that the metabolism of cotinine, the proximate metabolite of nicotine,
is significantly slower in black than in white cigarette smokers. To understand why the …