Effectiveness and safety of anti-BCMA chimeric antigen receptor T-cell treatment in relapsed/refractory multiple myeloma: a comprehensive review and meta-analysis …

D Hu, L Chen, D Yan, W Dong, M Chen… - Frontiers in …, 2023 - frontiersin.org
Background: Chimeric antigen receptor T cells treatment targeting B cell maturation antigen
(BCMA) is an emerging treatment option for relapsed/refractory multiple myeloma (RRMM) …

[HTML][HTML] The molecular perspective on the development of melanoma and genome engineering of T-cells in targeting therapy

F Hajibabaie, N Abedpoor, SH Javanmard… - Environmental …, 2023 - Elsevier
Melanoma, an aggressive malignant tumor originating from melanocytes in humans, is on
the rise globally, with limited non-surgical treatment options available. Recent …

Alloreactivity of allogeneic mesenchymal stem/stromal cells and other cellular therapies: a concise review

K Shah, N Shah, F Ghassemi, C Ly… - Stem Cells …, 2022 - Wiley Online Library
Cellular therapies, deemed live medicine, have brought a wave of new generation biological
therapies to treat previously untreatable diseases such as cancers and degenerative …

Leveraging biomaterials for enhancing T cell immunotherapy

Z Liao, W Zhang, H Zheng, Y Wang, J Yu, H Li… - Journal of Controlled …, 2022 - Elsevier
The dynamic roles of T cells in the immune system to recognize and destroy the infected or
mutated cells render T cell therapy a prospective treatment for a variety of diseases …

Chimeric antigen receptor-T cells: a pharmaceutical scope

A Hernández-López, MA Téllez-González… - Frontiers in …, 2021 - frontiersin.org
Cancer is among the leading causes of death worldwide. Therefore, improving cancer
therapeutic strategies using novel alternatives is a top priority on the contemporary scientific …

Intelligent Nanoplatform Integrating Macrophage and Cancer Cell Membrane for Synergistic Chemodynamic/Immunotherapy/Photothermal Therapy of Breast Cancer

S Zhang, W Chen, Y Zhou, X Zheng, Y Fu… - … Applied Materials & …, 2023 - ACS Publications
Cell membrane-coated nanoplatforms for drug delivery have garnered significant attention
due to their inherent cellular properties, such as immune evasion and homing abilities …

Graphdiyne oxide nanosheets exert anti-lymphoma effect by killing cancer stem cells and remodeling tumor microenvironment

J Li, Q Wang, H Lu, Y Han, L Jiang, W Qian, M Zhu… - Nano Today, 2022 - Elsevier
Inflammatory and immunosuppressive tumor microenvironment (TME) is responsible for
accelerating lymphoma initiation and progression. Graphdiyne oxide (GDYO) nanosheets …

Comprehensive clinical evaluation of CAR-T cell immunotherapy for solid tumors: a path moving forward or a dead end?

K Drougkas, K Karampinos, I Karavolias… - Journal of Cancer …, 2023 - Springer
Abstract Introduction Chimeric Antigen Receptor (CAR)-T cell therapy is a form of adoptive
cell therapy that has demonstrated tremendous results in the treatment of hematopoietic …

Treatment with living drugs: pharmaceutical aspects of CAR T cells

A Holzinger, H Abken - Pharmacology, 2022 - karger.com
Background: Adoptive therapy with genetically modified T cells achieves spectacular
remissions in advanced hematologic malignancies. In contrast to conventional drugs, this …

Cellular therapy updates in B-cell lymphoma: the state of the CAR-T

ZD Crees, A Ghobadi - Cancers, 2021 - mdpi.com
Simple Summary B-cell lymphomas are the most commonly occurring blood cancer and the
second leading cause of cancer-related death among blood cancers. Chemotherapy and …