Background Although nodal invasion represents one of the most powerful prognostic
indicators in colorectal cancer, marked heterogeneity exists within stage III patients …

Since the MOSAIC study, oxaliplatin-based adjuvant chemotherapy has been the standard
treatment of stage III colon cancer. Combination therapy with fluoropyrimidines and …

Background The 7th edition of the AJCC Cancer Staging Manual (AJCC-7) includes
substantial changes for colon cancer (CC), which are particularly complex in patients with …

AIM To analyze the survival trends in colorectal cancer (CRC) based on the different
classifications recommended by the seventh and eighth editions of the American Joint …

Pancreatic ductal adenocarcinoma (PDAC) represents the fourth cause of death in cancer
and has a 5-year survival of< 5%. Only about 15% of the patients present with a resectable …

Background IMP3 (insulinlike growth factor II mRNA-binding protein 3) is a newly identified
oncofetal RNA-binding protein that is involved in cell growth and cell migration during the …

The prognostic significance of identifying lymph node (LN) metastases following surgical
resection for colon and rectal cancer is well recognized and is reflected in accurate staging …

Background The most important prognostic factor in colonic cancer is the presence or
absence of regional lymph nodes metastases. The aim of this study was to evaluate the …

Objective: We analyzed 3 previously identified cut-off values of lymph node ratios (0.17,
0.41, and 0.69) in a large population-based collective of patients with colorectal cancer for …

Lymphadenectomy of colorectal cancer is a decisive factor for the prognostic and
therapeutic staging of the patient. For over 15 years, we have asked ourselves if the …