A review on evidence-based treatments for meibomian gland dysfunction

PY Lam, KC Shih, PY Fong, TCY Chan, ALK Ng… - Eye & contact …, 2020 - journals.lww.com
Objectives: To evaluate recent studies on available therapies for meibomian gland
dysfunction (MGD). Methods: A literature search on recent publications, within the last five …

NLRP3 Inflammasome as a Potential Therapeutic Target in Dry Eye Disease

D Zhuang, SL Misra, OO Mugisho… - International Journal of …, 2023 - mdpi.com
Dry eye disease (DED) is a multifactorial ocular surface disorder arising from numerous
interrelated underlying pathologies that trigger a self-perpetuating cycle of instability …

Latest evidences on meibomian gland dysfunction diagnosis and management

E Villani, L Marelli, A Dellavalle, M Serafino, P Nucci - The ocular surface, 2020 - Elsevier
Meibomian gland dysfunction (MGD) can be considered the leading cause of dry eye
disease (DED) and one of the most common ophthalmic disorders found in clinical practice …

Effect of a novel omega-3 and omega-6 fatty acid supplement on dry eye disease: A 3-month randomized controlled trial

A Ng, J Woods, T Jahn, LW Jones… - Optometry and Vision …, 2022 - journals.lww.com
PURPOSE This study aimed to determine the effect of daily intake of a novel combination of
essential fatty acids on signs and symptoms of DED. METHODS Participants with moderate …

Matrix metalloproteinase-9 in the pathophysiology and diagnosis of dry eye syndrome

SC Pflugfelder, F Bian, CS de Paiva - Metalloproteinases In …, 2017 - Taylor & Francis
Dry eye and tear dysfunction are common ocular disorders that cause cornea barrier
disruption resulting in a poorly lubricated and irregular cornea epithelium, eye irritation and …

[HTML][HTML] Current Advances in mechanisms and treatment of Dry eye Disease: toward Anti-inflammatory and immunomodulatory therapy and traditional Chinese …

J Ling, BCL Chan, MSM Tsang, X Gao… - Frontiers in …, 2022 - frontiersin.org
Dry eye is currently one of the most common ocular surface disease. It can lead to ocular
discomfort and even cause visual impairment, which greatly affects the work and quality of …

Ductal hyperkeratinization and acinar renewal abnormality: new concepts on pathogenesis of meibomian gland dysfunction

YL Du, X Peng, Y Liu, JS Wang, YF Ye, KK Xu… - Current Issues in …, 2023 - mdpi.com
Meibomian gland dysfunction (MGD) is a functional and morphological disorder of the
meibomian glands which results in qualitative or quantitative alteration in meibum secretion …

Free amino acids: an innovative treatment for ocular surface disease

D Rusciano, AM Roszkowska, C Gagliano… - European journal of …, 2016 - Elsevier
Amino acids are the basic constituents of living organisms, and have both a structural and
an active dynamic role in tissue and cell physiology. Human tears contain 23 amino acids …

[HTML][HTML] Fibroblast growth factor receptor 2 (FGFR2) is required for meibomian gland homeostasis in the adult mouse

LW Reneker, L Wang, RT Irlmeier… - … & Visual Science, 2017 - tvst.arvojournals.org
Purpose: Little is known about the signaling mechanisms controlling meibomian gland (MG)
homeostasis and the pathogenic processes leading to MG atrophy and dysfunction in dry …

[HTML][HTML] Intricate insights into immune response in dry eye disease

RP Kaur, B Gurnani, K Kaur - Indian Journal of Ophthalmology, 2023 - journals.lww.com
Dry eye disease (DED) is a complex disorder of the ocular surface with a loss of tear film
homeostasis, causing an imbalance in the tear–air interface and leading to ocular …