Calcium-dependent insulin resistance in hepatocytes: mathematical model

IV Dokukina, MV Yamashev, EA Samarina… - Journal of Theoretical …, 2021 - Elsevier
Hepatocyte insulin resistance is one of the early factors of developing type II diabetes. If
insulin resistance is treated early, type II diabetes could be prevented. In recent years …

Exposure to maternal cafeteria diets during the suckling period has greater effects on fat deposition and Sterol Regulatory Element Binding Protein-1c (SREBP-1c) …

MA Vithayathil, JR Gugusheff, ZY Ong… - Nutrition & …, 2018 - Springer
Background While the adverse metabolic effects of exposure to obesogenic diets during
both the prenatal and early postnatal period are well established, the relative impact of …

The 24-hour respiratory quotient predicts energy intake and changes in body mass

KA Longo, S Charoenthongtrakul… - American Journal …, 2010 - journals.physiology.org
To define the relationship between the respiratory quotient (RQ) and energy intake (EI) and
to determine the impact of spontaneous locomotor activity (LMA) in the development of diet …

Gsα deficiency in skeletal muscle leads to reduced muscle mass, fiber-type switching, and glucose intolerance without insulin resistance or deficiency

M Chen, HZ Feng, D Gupta, J Kelleher… - … of Physiology-Cell …, 2009 - journals.physiology.org
The ubiquitously expressed G protein α-subunit Gsα is required for receptor-stimulated
intracellular cAMP responses and is an important regulator of energy and glucose …

An 8-week high-fat diet induces obesity and insulin resistance with small changes in the muscle transcriptome of C57BL/6J mice

J de Wilde, E Smit, R Mohren, MV Boekschoten… - Lifestyle …, 2010 - karger.com
Background: Skeletal muscle is responsible for most of the insulin-stimulated glucose
uptake and metabolism. Therefore, it plays an important role in the development of insulin …

Enhanced lipid oxidation and maintenance of muscle insulin sensitivity despite glucose intolerance in a diet-induced obesity mouse model

KE Trajcevski, HM O'Neill, DC Wang, MM Thomas… - PLoS …, 2013 - journals.plos.org
Background Diet-induced obesity is a rising health concern which can lead to the
development of glucose intolerance and muscle insulin resistance and, ultimately, type II …

High fat diet-induced changes in mouse muscle mitochondrial phospholipids do not impair mitochondrial respiration despite insulin resistance

J Hoeks, J de Wilde, MFM Hulshof, SAA van den Berg… - PloS one, 2011 - journals.plos.org
Background Type 2 diabetes mellitus and muscle insulin resistance have been associated
with reduced capacity of skeletal muscle mitochondria, possibly as a result of increased …

Effect of rumen-protected fat on performance, carcass characteristics and beef quality of the progeny from Nellore cows fed by different planes of nutrition during …

GD Ramírez-Zamudio, WFG da Cruz, JP Schoonmaker… - Livestock Science, 2022 - Elsevier
The objective of this research was to evaluate the performance, carcass traits, meat quality
and the expression of myogenic and lipogenic genes in muscle of steers finished with or …

Differential effects of a saturated and a monounsaturated fatty acid on MHC class I antigen presentation

SR Shaikh, D Mitchell, E Carroll, M Li… - Scandinavian …, 2008 - Wiley Online Library
Lipid overload, associated with metabolic disorders, occurs when fatty acids accumulate in
non‐adipose tissues. Cells of these tissues use major histocompatibility complex (MHC) …

From the black widow spider to human behavior: Latrophilins, a relatively unknown class of G protein‐coupled receptors, are implicated in psychiatric disorders

AF Martinez, M Muenke… - American Journal of …, 2011 - Wiley Online Library
The findings of a recent study associate LPHN3, a member of the latrophilin family, with an
increased risk of developing attention deficit/hyperactivity disorder (ADHD), the most …