Adipophilin protein expression in muscle–a possible protective role against insulin resistance

J de Wilde, E Smit, FJM Snepvangers… - The FEBS …, 2010 - Wiley Online Library
Adipophilin is a 50 kDa protein that belongs to the PAT family (perilipin, adipophilin, TIP47,
S3‐12 and OXPAT), which comprises proteins involved in the coating of lipid droplets. Little …

Effect of high‐fat diet on isometric, concentric and eccentric contractile performance of skeletal muscle isolated from female CD‐1 mice

J Tallis, RS James, ELJ Eyre, SP Shelley… - Experimental …, 2024 - Wiley Online Library
Despite evidence inferring muscle and contractile mode‐specific effects of high‐fat diet
(HFD), no study has yet considered the impact of HFD directly on eccentric muscle function …

[HTML][HTML] Glut4 突变调控脂肪重分布及肌纤维重塑的机制研究

谢宁, 张凯艺, 阮进学, 陶聪, 吴添文, 王彦芳, 杨述林 - 畜牧兽医学报, 2021 - xml-data.org
旨在探讨Glut4 基因突变后骨骼肌能量代谢及肌纤维转化的分子机制. 本研究利用CRISPR/Cas9
技术构建Glut4 Q177L 突变鼠. 选取22 周龄健康的野生雄鼠和Glut4 Q177L 突变雄鼠 …

Brain in situ hybridization maps as a source for reverse-engineering transcriptional regulatory networks: Alzheimer's disease insights

GK Acquaah-Mensah, RC Taylor - Gene, 2016 - Elsevier
Microarray data have been a valuable resource for identifying transcriptional regulatory
relationships among genes. As an example, brain region-specific transcriptional regulatory …

Transcriptome profiling analysis reveals the role of latrophilin in controlling development, reproduction and insecticide susceptibility in Tribolium castaneum

S Gao, W Xiong, L Wei, J Liu, X Liu, J Xie, X Song, J Bi… - Genetica, 2018 - Springer
Abstract Latrophilin of Tribolium castaneum (Tclph) has been reported to play crucial roles in
growth, development and reproduction. However, the regulatory mechanism of Tclph …

Antioxidant enzymes induced by repeated intake of excess energy in the form of high-fat, high-carbohydrate meals are not sufficient to block oxidative stress in healthy …

S Lim, H Won, Y Kim, M Jang, KR Jyothi… - British Journal of …, 2011 - cambridge.org
It has been reported that high-fat, high-carbohydrate (HFHC) meals increase oxidative stress
and inflammation. We examined whether repeated intake of excess energy in the form of …

Similar changes in muscle lipid metabolism are induced by chronic high‐fructose feeding and high‐fat feeding in C57 BL/J6 mice

GY Song, LP Ren, SC Chen, C Wang… - Clinical and …, 2012 - Wiley Online Library
The aim of the present study was to investigate the effects of high fructose and high fat
feeding on muscle lipid metabolism and to illustrate the mechanisms by which the two …

The embryonic genes Dkk3, Hoxd8, Hoxd9 and Tbx1 identify muscle types in a diet-independent and fiber-type unrelated way

J de Wilde, MFM Hulshof, MV Boekschoten, P de Groot… - BMC genomics, 2010 - Springer
Background The mouse skeletal muscle is composed of four distinct fiber types that differ in
contractile function, number of mitochondria and metabolism. Every muscle type has a …

The skeletal muscle transcriptome profile of elderly men with metabolic syndrome based on weighted gene co-expression network analysis

X Ge, Q Wang, T Yao, J Xie, C Zhang, LC Xu - Obesity Facts, 2023 - karger.com
Introduction: This study aimed to understand the transcriptome characteristics of the skeletal
muscle of elderly (EL) men with metabolic syndrome (MS) and to find the hub genes and …

Obesity-induced discrepancy between contractile and metabolic phenotypes in slow-and fast-twitch skeletal muscles of female obese Zucker rats

LM Acevedo, AI Raya, R Ríos… - Journal of Applied …, 2017 - journals.physiology.org
A clear picture of skeletal muscle adaptations to obesity and related comorbidities remains
elusive. This study describes fiber-type characteristics (size, proportions, and oxidative …