The calcaneus is a rare location for the occurrence and development of primary tumour
types. Clinicians are unfamiliar with calcaneal tumour types, which may result in a delay in …

The overall incidence of osteosarcoma is low. However, the occurrence of osteosarcoma in
a setting of multiple primary tumours is not infrequent, although population-based incidence …

Werner syndrome (WS), adult progeria, is more common in Japan than elsewhere. It
predisposes to osteosarcoma (OS) and five other rare tumors. To determine if and how OS is …

In 1998, we reported a unique case of an osteosarcoma of the calcaneus treated with a
custom calcaneal prosthesis. 3 Three years after the surgery, the patient was able to bear …

BACKGROUND Partially due to the rare occurrence of soft tissue and osteogenic sarcomas
in the general population, scant attention has been given to their hereditary etiology. Their …

Abstract Background and Objectives Malignant tumors of the calcaneus are rare but pose a
treatment challenge. Aims:(1) describe the demographics of calcaneal malignancies in a …

Purpose Tumours of the calcaneus are exceedingly rare and the correct diagnosis is often
missed. X-rays are the standard clinical examination tool and therefore we wanted to …

Werner syndrome (WS) is the canonical adult human progeroid ('premature aging')
syndrome. Patients with this autosomal recessive Mendelian disorder display constitutional …

For the purpose of examining the characteristics of dyslipidemia and fatty liver in patients
with Werner syndrome in Japan in recent years, we searched all case reports of Japanese …

Abstract Background The Werner syndrome protein (WRN) belongs to the RecQ family of
helicases and its loss of function results in the premature aging disease Werner syndrome …