In the immunopathogenesis of systemic lupus erythematosus (SLE), there is a dysregulation
of specific immune cells, including T cells. The metabolic reprogramming in T cells causes …

Atherosclerosis is a chronic disease resulting from an impaired lipid and immune
homeostasis, where the interaction between innate and adaptive immune cells leads to the …

The gastrointestinal microenvironment, dominated by dietary compounds and the
commensal bacteria, is a major driver of intestinal CD4+ T helper (Th) cell differentiation …

Apolipoproteins play key roles in normal lipid homeostasis by transporting cholesterol and
lipids between cells. Apolipoproteins, such as apolipoprotein E (apoE), apolipoprotein AI …

Background and aims Hypercholesterolemia is frequently diagnosed in patients with primary
biliary cholangitis (PBC). However, its association with the prognosis and lipid metabolism is …

Steady-state expression quantitative trait loci (eQTLs) explain only a fraction of disease-
associated loci identified through genome-wide association studies (GWASs), while eQTLs …

Background and aims Circulating levels of oxidized lipoprotein (oxLDL) correlate with
myocardial infarction risk and atherosclerosis severity. Our previous study demonstrates that …

Primary immune thrombocytopenia (ITP) is an acquired autoimmune disease. Cellular and
systemic lipid metabolism plays a significant role in the regulation of immune cell activities …

Obesity-derived disturbances in fatty acid and cholesterol metabolism are linked to
numerous diseases, including various types of malignancy. In tumor cells, metabolic …

Numerous cardiovascular disorders have atherosclerosis as their pathological
underpinning. Numerous studies have demonstrated that, with the aid of pattern recognition …