Neuropathic pain: From actual pharmacological treatments to new therapeutic horizons

M Thouaye, I Yalcin - Pharmacology & Therapeutics, 2023 - Elsevier
Neuropathic pain, caused by a lesion or disease affecting the somatosensory system, affects
between 3 and 17% of the general population. The treatment of neuropathic pain is …

Shedding light on neuropathic pain: Current and emerging tools for diagnosis, screening, and quantification

A Hamdan, R Galvez, M Katati - SAGE Open Medicine, 2024 - journals.sagepub.com
Ensuring the proper management of neuropathic pain is a contemporary challenge for
professionals who care for patients with this type of pain. The estimated prevalence of …

Neuropathic Pain in the Emergency Setting: Diagnosis and Management

PE Doneddu, U Pensato, A Iorfida, C Alberti… - Journal of Clinical …, 2023 - mdpi.com
Neuropathic pain, traditionally considered a chronic condition, is increasingly encountered
in the emergency department (ED), accounting for approximately 20% of patients presenting …

Diagnosis and management of neuropathic pain in spine diseases

J Bielewicz, M Kamieniak, M Szymoniuk, J Litak… - Journal of Clinical …, 2023 - mdpi.com
Neuropathic pain is generally defined as a non-physiological pain experience caused by
damage to the nervous system. It can occur spontaneously, as a reaction to a given stimulus …

Methyl ferulic acid alleviates neuropathic pain by inhibiting nox4-induced ferroptosis in dorsal root ganglia neurons in rats

T Liu, R Wang, W Qi, L Jia, K Ma, J Si, J Yin… - Molecular …, 2023 - Springer
Neuropathic pain is a disease that has become one of the major public health problems and
a global burden. Nox4-induced oxidative stress can lead to ferroptosis and neuropathic …

A review of the therapeutic targeting of SCN9A and Nav1. 7 for pain relief in current human clinical trials

A Dormer, M Narayanan, J Schentag… - Journal of Pain …, 2023 - Taylor & Francis
Introduction There is a great need to find alternative treatments for chronic pain which have
become a healthcare problem. We discuss current therapeutic targeting Nav1. 7. Areas …

[HTML][HTML] The dorsal root ganglion as a target for neurorestoration in neuropathic pain

G Estivill-Torrús, AB Martínez-Padilla… - Neural Regeneration …, 2024 - journals.lww.com
Neuropathic pain is a severe and chronic condition widely found in the general population.
The reason for this is the extensive variety of damage or diseases that can spark this …

Recent progress in gels for neuropathic pain

C Pușcașu, A Zanfirescu, S Negreș - Gels, 2023 - mdpi.com
Neuropathic pain is a complex and debilitating condition that affects millions of people
worldwide. While several treatment options are available, they often have limited efficacy …

Ion Channel Genes in Painful Neuropathies

M Ślęczkowska, K Misra, S Santoro, MM Gerrits… - Biomedicines, 2023 - mdpi.com
Neuropathic pain (NP) is a typical symptom of peripheral nerve disorders, including painful
neuropathy. The biological mechanisms that control ion channels are important for many cell …

Black-white hole pattern: an investigation on the automated chronic neuropathic pain detection using EEG signals

I Tasci, M Baygin, PD Barua, A Hafeez-Baig… - Cognitive …, 2024 - Springer
Electroencephalography (EEG) signals provide information about the brain activities, this
study bridges neuroscience and machine learning by introducing an astronomy-inspired …