Leprosy: treatment, prevention, immune response and gene function

X Li, Y Ma, G Li, G Jin, L Xu, Y Li, P Wei… - Frontiers in …, 2024 - frontiersin.org
Since the leprosy cases have fallen dramatically, the incidence of leprosy has remained
stable over the past years, indicating that multidrug therapy seems unable to eradicate …

Vitamin D receptor gene polymorphism predicts the outcome of multidisciplinary rehabilitation in multiple sclerosis patients

FR Guerini, C Agliardi, L Oreni, E Groppo… - International Journal of …, 2023 - mdpi.com
Better knowledge about the possible role of genetic factors in modulating the response to
multiple sclerosis (MS) treatment, including rehabilitation, known to promote neural …

Association between FokI polymorphism of vitamin D receptor gene and lumbar spine disc degeneration: a systematic review and meta-analysis

RG Castillo-Avila, TB González-Castro… - American Journal of …, 2021 - journals.lww.com
Objective The aim of the present meta-analysis was to explore the association between FokI
polymorphism of the vitamin D receptor gene and lumbar spine disc degeneration. Design …

The influence of vitamin D receptor gene polymorphisms in spondyloarthritis

JSF Neves, JEL Visentainer, DMS Reis… - International journal …, 2020 - Wiley Online Library
Spondyloarthritis (SpA) is an inflammatory rheumatic disease related to low bone mineral
density. Because vitamin D plays an important role in bone metabolism and immune system …

IL17F: A Possible Risk Marker for Spondyloarthritis in HLA-B*27 Negative Brazilian Patients

JSF Neves, JEL Visentainer, DMS Reis… - Journal of Personalized …, 2021 - mdpi.com
HLA-B* 27 is an important marker for spondyloarthritis (SpA), however, many SpA patients
are HLA-B* 27 negative. Thus, the aim of this study was to investigate the influence of IL17 …

Association of the polymorphism of the vitamin D receptor gene (VDR) with the risk of leprosy in the Brazilian Amazon

JLP Paz, MPSCA Silvestre, LS Moura… - Bioscience …, 2021 - portlandpress.com
The transmission and evolution of leprosy depends on several aspects, including
immunological and genetic factors of the host, as well as genetic factors of Mycobacterium …

Fever of Unknown Origin, Wasting Syndrome and Bone Marrow Involvement: A Leprosy Case Report

MAO Santana, WVT da Costa, IC Celestino… - Frontiers in …, 2022 - frontiersin.org
Mycobacterium leprae, the etiologic agent of leprosy, is an acid-fast-staining and slow-
growing bacilli that infect macrophages and Schwann cells individually or through forming …

The relationship between single nucleotide polymorphisms and skin cancer susceptibility: A systematic review and network meta-analysis

L Zhang, É Pozsgai, Y Song, J Macharia… - Frontiers in …, 2023 - frontiersin.org
Background Single nucleotide polymorphisms (SNPs) interfere with the function of certain
genes and thus may influence the probability of skin cancer. The correlation between SNPs …

Research on the application of molecular epidemiology in the prediction and prognosis of cancer

Z Lu - 2024 - pea.lib.pte.hu
Background: Molecular epidemiology is a novel subject that integrates molecular biology
and basic epidemiology. However, how it is used in specific practical studies, and how it …

Prevalensi polimorfisme gen reseptor vitamin D FokI Rs2228570 pada penderita kusta tipe multibasiler

LMM Rusyati, NP Krisnaputri… - Intisari Sains …, 2024 - mailgate.isainsmedis.id
Introduction: Leprosy is still a health problem in Indonesia. Vitamin D receptors are known to
affect leprosy. Polymorphism of the VDR gene can lead to deregulation of vitamin D. The …