The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Diabetic kidney disease (DKD) causes the greatest proportion of end-stage renal disease
(ESRD)–related mortality and has become a high concern in patients with diabetes mellitus …

Context Burosumab was developed as a treatment option for patients with the rare, lifelong,
chronically debilitating, genetic bone disease X-linked hypophosphatemia (XLH). Objective …

Background The links between chronic kidney disease (CKD) and the high burden of
cardiovascular disease remain unclear. We aimed to explore the association between …

X-chromosomal hypophosphatemia is a disease in which too much phosphate is excreted in
the urine, which should actually be recovered in the kidney from the pre-urine. This leads to …

In recent years, new therapies for the treatment of rare pediatric bone disorders have
emerged, guided by an increasing understanding of the genetic and molecular etiology of …

Background: Genome-wide association studies (GWAS) have identified numerous genetic
loci associated with mineral metabolism (MM) markers but have exclusively focused on …

The fibroblast growth factors (FGF) family is composed of 22 structurally related peptides,
which have a wide spectrum of cellular functions, including cell growth, embryonic …

A case of severe x-linked hypophosphatemia caused by a novel phex mutation | Pediatric
Oncall Journal Pediatric Oncall facebook twitter youtube instagram rss ISSN - 0973-0958 Home …

Antecedentes y objetivo: Las tubulopatías primarias son enfermedades raras, que se
presentan habitualmente en la edad pediátrica. Los avances recientes en el diagnóstico …