Skin is an important organ that mainly functions as a barrier. Skin diseases can damage a
person's self-confidence and reduce their willingness to socialize, as well as their social …

Alterations in the innate and adaptive immunity underpin psoriasis pathophysiology, with the
Th17 cells subset now recognized as the fundamental cells in the key controlling pathway …

Cellular sources of IL-23 and IL-17A driving skin inflammation in psoriasis remain unclear.
Using high-dimensional unsupervised flow cytometry analysis, mononuclear phagocytes …

Dermatophytoses (ringworms) are among the most frequent skin infections and are a highly
prevalent cause of human disease worldwide. Despite the incidence of these superficial …

IL-17 was discovered nearly 30 yr ago, but it has only been recently appreciated that a key
function of this cytokine is to orchestrate cellular and organismal metabolism. Indeed …

Psoriasis and psoriatic arthritis are chronic immune-mediated disorders with involvement of
interleukin (IL)-17 cytokines in their pathogenesis. IL-17A has been considered to be the …

The AHR is an environmental sensor and transcription factor activated by a variety of man-
made and natural ligands, which has recently emerged as a critical regulator of homeostasis …

Psoriatic disease is a chronic, systemic immune‐mediated inflammatory disorder comprising
three major domains, skin, vascular and bone/joint inflammation. It is known for a long time …

Immune-mediated inflammation contributes to the development of psoriasis. However, long-
term treatment with global immunosuppressive agents may cause a variety of side effects …

CCCH zinc finger proteins resolve immune responses by degrading the mRNAs of
inflammatory cytokines such as tumor necrosis factor (TNF) and interleukin (IL)-6. Here we …