Molecular subtypes of colorectal cancer: mechanisms involved in tumor progression and immune evasion

R Mena-Osuna - 2021 - helvia.uco.es
Molecular classification of colorectal cancer (CRC) has led to the identification of four
Consensus Molecular Subtypes (CMS), with different immune microenvironments linked to …

[PDF][PDF] Análisis individual de los cambios metabólicos transcripcionales en pacientes con cáncer de colon y su asociación con el perfil inflamatorio tumoral.

C Fernández Pomares - 2021 - cdigital.uv.mx
A pesar de que la inmunoterapia ha mostrado resultados esperanzadores en el tratamiento
del cáncer, su efectividad puede estar comprometida por el metabolismo tumoral. Conocer …

The Diagnostic and Prognostic Value of BEN-Domain (BEND) Family Genes in Gastric Cancer

J Fan, M Yang, C Liang, C Liang, J Guo - 2022 - researchsquare.com
BEND (BEN domain-containing protein) is a domain protein-coding gene, whose abnormal
expression is related to the occurrence of malignant tumors. But studies on gastric cancer …

An immune-associated gene prognostic index risk model for stomach adenocarcinoma

W Xue, B Dong, Y Wang, Y Xie, Q Xue, Z Gong, C Zhu… - 2021 - researchsquare.com
Background Stomach adenocarcinoma (STAD) is one of the most common malignant tumors
worldwide. In this study, we attempt to construct a valid immune-associated gene prognostic …

[PDF][PDF] им. НН Блохина» Минздрава России (Москва, Россия) 2 Факультет непрерывного медицинского образования

МЮ Федянин, ЕО Игнатова, АА Трякин - 2021 - practical-oncology.ru
73 Т. 22, № 1–2021 прогностическому течению, но и позволить индивидуализировать
лечение. Однако полученные в клинических исследованиях данные, по крайней мере …

Metastasis and cancer stem cell markers identify two colorectal cancer subtypes with different molecular and clinical features

B Alsaihati - 2020 - search.proquest.com
Colorectal cancer (CRC) is among the top prevalent cancer types with lethal outcome in the
United States and worldwide. CRC inter-tumor heterogeneity highlights the importance of …

[PDF][PDF] Implications of Intratumor Heterogeneity on Consensus Molecular Subtype (CMS) in Colorectal Cancer. Cancers 2021, 13, 4923

S Chowdhury, M Hofree, K Lin, D Maru, S Kopetz… - 2021 - academia.edu
The implications of intratumor heterogeneity on the four consensus molecular subtypes
(CMS) of colorectal cancer (CRC) are not well known. Here, we use single-cell RNA …

[PDF][PDF] Research Article Major Histocompatibility Complex Genes as Therapeutic Opportunity for Immune Cold Molecular Cancer Subtypes

P Karpiński, Ł Łaczmański, MM Sąsiadek - ppm.umw.edu.pl
Current immunotherapies are effective only in a subset of patients, likely due to several
factors including defects in tumor cell antigen presentation, decreased response to immune …

Identification of CXCL8 as an Immune Microenvironment Regulator of Colorectal Cancer: A Bioinformatics Study Based on Cancer Genome Atlas and Gene …

Y Shao, S Gao, M Cheng, J Zheng, T Yang, T Li… - 2020 - researchsquare.com
Background At present, a lack of knowledge of the molecular mechanisms underlying the
genesis and progression of colorectal cancer (CRC) exists. This is one of the reasons for …