[HTML][HTML] NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: molecular mechanisms and possible therapeutic approaches

F Sivandzade, S Prasad, A Bhalerao, L Cucullo - Redox biology, 2019 - Elsevier
Electrophiles and reactive oxygen species (ROS) play a major role in modulating cellular
defense mechanisms as well as physiological functions, and intracellular signaling …

Melatonin and inflammation—Story of a double‐edged blade

R Hardeland - Journal of pineal research, 2018 - Wiley Online Library
Melatonin is an immune modulator that displays both pro‐and anti‐inflammatory properties.
Proinflammatory actions, which are well documented by many studies in isolated cells or …

Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials

AK Tripathi, AK Ray, SK Mishra - Beni-Suef university journal of basic and …, 2022 - Springer
Background Piperine is a type of amide alkaloid that exhibits pleiotropic properties like
antioxidant, anticancer, anti-inflammatory, antihypertensive, hepatoprotective …

Pathophysiology and therapeutic perspectives of oxidative stress and neurodegenerative diseases: a narrative review

M Rekatsina, A Paladini, A Piroli, P Zis, JV Pergolizzi… - Advances in …, 2020 - Springer
Introduction Neurodegeneration is the term describing the death of neurons both in the
central nervous system and periphery. When affecting the central nervous system, it is …

Fermented soy products and their potential health benefits: A review

FG do Prado, MGB Pagnoncelli, GV de Melo Pereira… - Microorganisms, 2022 - mdpi.com
In the growing search for therapeutic strategies, there is an interest in foods containing
natural antioxidants and other bioactive compounds capable of preventing or reversing …

Ionizing radiation as a source of oxidative stress—the protective role of melatonin and vitamin D

J Nuszkiewicz, A Woźniak… - International journal of …, 2020 - mdpi.com
Ionizing radiation (IR) has found widespread application in modern medicine, including
medical imaging and radiotherapy. As a result, both patients and healthcare professionals …

Directional induction of neural stem cells, a new therapy for neurodegenerative diseases and ischemic stroke

L Nie, D Yao, S Chen, J Wang, C Pan, D Wu… - Cell Death …, 2023 - nature.com
Due to the limited capacity of the adult mammalian brain to self-repair and regenerate,
neurological diseases, especially neurodegenerative disorders and stroke, characterized by …

Seizure-induced oxidative stress in status epilepticus: is antioxidant beneficial?

TK Lin, SD Chen, KJ Lin, YC Chuang - Antioxidants, 2020 - mdpi.com
Epilepsy is a common neurological disorder which affects patients physically and mentally
and causes a real burden for the patient, family and society both medically and …

GLP-1 mimetics and cognition

H Yaribeygi, A Rashidy-Pour, SL Atkin, T Jamialahmadi… - Life Sciences, 2021 - Elsevier
Abstract Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of antidiabetic drugs
that improve the glycaemia via several molecular pathways. Recent evidence suggest that …

Ferulic acid: An extraordinarily neuroprotective phenolic acid with anti-depressive properties

X Dong, R Huang - Phytomedicine, 2022 - Elsevier
Background Depression, one of the most common mental illnesses and mood disorder
syndromes, can seriously harm physical and mental health. As the pathophysiology of …