Exosomal circular RNAs: A chief culprit in cancer chemotherapy resistance

X Guo, C Gao, DH Yang, S Li - Drug Resistance Updates, 2023 - Elsevier
Chemotherapy is one of the primary treatments for malignant tumors. However, the acquired
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …

Crosstalk between long noncoding RNA and microRNA in Cancer

R Bhattacharjee, N Prabhakar, L Kumar… - Cellular Oncology, 2023 - Springer
Abstract miRNAs and lncRNAs play a central role in cancer-associated gene regulations.
The dysregulated expression of lncRNAs has been reported as a hallmark of cancer …

Myco-synthesis of silver nanoparticles and their bioactive role against pathogenic microbes

A Abdel-Hadi, D Iqbal, R Alharbi, S Jahan, O Darwish… - Biology, 2023 - mdpi.com
Simple Summary The relatively high prevalence of microbial infections and the rising
resistance to traditional antibiotics are the causes of the need for revolutionary antibiotics …

Multitargeted virtual screening and molecular simulation of natural product-like compounds against GSK3β, NMDA-receptor, and BACE-1 for the management of …

D Iqbal, MT Rehman, MF Alajmi, M Alsaweed… - Pharmaceuticals, 2023 - mdpi.com
The complexity of Alzheimer's disease (AD) and several side effects of currently available
medication inclined us to search for a novel natural cure by targeting multiple key regulatory …

Multi‐omics data reveals novel impacts of human papillomavirus integration on the epigenomic and transcriptomic signatures of cervical tumorigenesis

X Zeng, Y Wang, B Liu, X Rao, C Cao… - Journal of Medical …, 2023 - Wiley Online Library
Integration of human papilloma virus (HPV) DNA into the human genome may progressively
contribute to cervical carcinogenesis. To explore how HPV integration affects gene …

Activating STING/TBK1 suppresses tumor growth via degrading HPV16/18 E7 oncoproteins in cervical cancer

X Huang, L Huo, B Xiao, Y Ouyang, F Chen… - Cell Death & …, 2024 - nature.com
Cervical cancer is the most common gynecologic cancer, etiologically related to persistent
infection of human papillomavirus (HPV). Both the host innate immunity system and the …

[HTML][HTML] Promise of dostarlimab in cancer therapy: Advancements and cross-talk considerations

Q Babar, A Saeed, S Murugappan, D Dhumal… - Drug Discovery …, 2023 - Elsevier
In recent years, immunotherapy for cancer treatment using monoclonal antibodies has
shown clinical success, particularly with programmed cell death protein 1 (PD-1) and its …

JAK/STAT signaling and Cervical Cancer: from the cell surface to the Nucleus

A Valle-Mendiola, A Gutiérrez-Hoya, I Soto-Cruz - Genes, 2023 - mdpi.com
The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling
pathway constitutes a rapid signaling module from the cell surface to the nucleus, and …

Human papilloma virus: an unraveled enigma of universal burden of malignancies

I Khan, R Harshithkumar, A More, A Mukherjee - Pathogens, 2023 - mdpi.com
HPV, or Human Papilloma Virus, has been the primary causative agent of genital warts and
cervical cancer worldwide. It is a sexually transmitted infection mainly affecting women of …

Human papillomavirus 16 E6/E7 contributes to immune escape and progression of cervical cancer by regulating miR-142–5p/PD-L1 axis

J Ling, Q Sun, Q Tian, H Shi, H Yang, J Ren - Archives of Biochemistry and …, 2022 - Elsevier
Persistent infection of human papillomavirus (HPV) and immune escape are the main
causes of cervical cancer. E6/E7 encoded by HPV16 may be closely related to …