SUMMARY β-Lactam antibiotics have been widely used as therapeutic agents for the past
70 years, resulting in emergence of an abundance of β-lactam-inactivating β-lactamases …

Klebsiella pneumoniae is an opportunistic bacterial pathogen known for its high frequency
and diversity of antimicrobial resistance (AMR) genes. In addition to being a significant …

Surveillance studies have shown that OXA-48-like carbapenemases are the most common
carbapenemases in Enterobacterales in certain regions of the world and are being …

Objectives The spread of carbapenem-resistant Enterobacteriaceae (CRE) in healthcare
settings challenges clinicians worldwide. However, little is known about dissemination of …

Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …

Multidrug resistant (MDR) Gram-negative bacteria have been increasingly reported in
humans, companion animals and farm animals. The growing trend of plasmid-mediated …

Carbapenem-resistant Enterobacterales (CRE) are a growing threat to human health
worldwide. CRE often carry multiple resistance genes that limit treatment options and …

Carbapenemase-producing Enterobacteriaceae (CPE) contribute significantly to the global
public health threat of antimicrobial resistance. OXA-48 and its variants are unique …

Abstract The Indian Council of Medical Research, in 2013, initiated the Antimicrobial
Resistance Surveillance & Research Network (AMRSN) to enable compilation of data on six …

The global burden of bacterial resistance remains one of the most serious public health
concerns. Infections caused by multidrug-resistant (MDR) bacteria in critically ill patients …