Background Angiogenesis is the formation of new vascular networks from preexisting ones
through the migration and proliferation of differentiated endothelial cells. Available evidence …

Background: CXCL12 (SDF1) is reported to promote cancer progression in several
preclinical models and this is corroborated by the analysis of human tissue specimens …

Interleukin-1 receptor type 2 (IL1R2) acts as a decoy receptor of exogenous IL-1; however,
its intracellular activity is poorly understood. We previously demonstrated that IL1R2 …

The mammary gland hosts a microbiota, which differs between malignant versus normal
tissue. We found that aerosolized antibiotics decrease murine mammary tumor growth and …

Background The neutrophil–lymphocyte ratio (NLR) is associated with a poor prognosis in
many cancers but the biological mechanisms involved are unknown. Since cytokines and …

Even though significant improvements in the treatment of colorectal cancer (CRC) have
been made in recent years, survival rates for metastatic colorectal cancer (mCRC) are poor …

High expectations are placed upon anti-angiogenic compounds for metastatic colorectal
cancer (mCRC), the first malignancy for which such type of treatment has been approved …

Simple Summary In this review, we aim to analyze the molecular bases of angiogenesis in
metastatic colorectal cancer (mCRC) and to provide an overview of potential predictive …

Novel predictive biomarkers are needed to improve patient selection and optimize the use of
bevacizumab (B) in metastatic colorectal cancer. We analyzed the potential of five circulating …

Wound healing fluid that originates from breast surgery increases the aggressiveness of
cancer cells that remain after the surgery. We determined the effects of the extent of surgery …