EMT‐cancer cells‐derived exosomal miR‐27b‐3p promotes circulating tumour cells‐mediated metastasis by modulating vascular permeability in colorectal cancer

R Dou, K Liu, C Yang, J Zheng, D Shi… - Clinical and …, 2021 - Wiley Online Library
Background Metastasis is the main cause of death in colorectal cancer (CRC). Circulating
tumour cells (CTCs) are regarded as the precursor cells of metastasis. The CTCs, which …

Research progress of nanocarriers for gene therapy targeting abnormal glucose and lipid metabolism in tumors

X Zeng, Z Li, C Zhu, L Xu, Y Sun, S Han - Drug delivery, 2021 - Taylor & Francis
In recent years, the incidence of various types of tumors has gradually increased, and it has
also been found that there is a certain correlation between abnormal glucose and lipid …

[HTML][HTML] LncRNA LIMT (LINC01089) contributes to sorafenib chemoresistance via regulation of miR-665 and epithelial to mesenchymal transition in hepatocellular …

J Sun, X Zheng, B Wang, Y Cai, L Zheng… - Acta Biochimica et …, 2022 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most malignant tumors worldwide and HCC
patients often develop drug resisitene. Long non-coding RNAs (LncRNAs) are closely …

FAK-LINC01089 negative regulatory loop controls chemoresistance and progression of small cell lung cancer

X Wang, X Li, L Niu, F Lv, T Guo, Y Gao, Y Ran… - Oncogene, 2024 - nature.com
The focal adhesion kinase (FAK) tyrosine kinase is activated and upregulated in multiple
cancer types including small cell lung cancer (SCLC). However, FAK inhibitors have shown …

LncRNA-LINC01089 inhibits lung adenocarcinoma cell proliferation and promotes apoptosis via sponging miR-543

Y Xu, L Lin, D Lv, S Yan, S He, H Ge - Tissue and Cell, 2021 - Elsevier
LINC01089, a newly discovered long non-coding RNA (lncRNA), has been reported to
inhibit the progression of various types of cancers. This study aimed to characterize …

Integrated analysis of necroptosis-related lncRNAs for prognosis and immunotherapy of patients with pancreatic adenocarcinoma

J Mo, Z Cui, Q Wang, W Zhang, J Li, S Wu… - Frontiers in …, 2022 - frontiersin.org
Accumulating studies have revealed that necroptosis plays a vital role in the occurrence and
development of pancreatic adenocarcinoma (PAAD). We aimed to construct a prognostic …

LINC01089 suppresses lung adenocarcinoma cell proliferation and migration via miR-301b-3p/STARD13 axis

Y Qian, Y Zhang, H Ji, Y Shen, L Zheng… - BMC Pulmonary …, 2021 - Springer
Background Lung adenocarcinoma (LUAD) is one of the most common cancers with high
morbidity and mortality worldwide. Long non-coding RNAs (lncRNAs) serve as tumor …

LINC01089 blocks malignant progression of thyroid cancer by binding miR-27b-3p to enhance the FBLN5 protein level

YQ Pan, KS Huang, TH Chong, JY Li - Discover Oncology, 2022 - Springer
LINC01089 suppresses the malignant progression of breast, colorectal, and non-small cell
lung cancers. However, the function of LINC01089 in thyroid cancer has not yet been …

The long non-coding RNA LIMT inhibits metastasis of hepatocellular carcinoma and is suppressed by EGF signaling

Y Hu, H Li, H Zhang, Q Tang, G Zhang, X Li… - Molecular Biology …, 2022 - Springer
Background The long non-coding RNA LIMT (lncRNA inhibiting metastasis) acts as a tumor
suppressor factor in some cancers. However, the biological role of LIMT in hepatocellular …