The frequent metastasis of gastric cancer (GC) complicates the cure and therefore the
development of effective diagnostic and therapeutic approaches is urgently necessary. In …

Gastric cancer (GC) is a malignant cancer of the digestive tract and is a life-threatening
disease worldwide. Ferroptosis is a newly discovered form of regulated cell death, which …

Drugs, which treat various diseases, are essential for human health. However, developing
new drugs is quite laborious, time-consuming, and expensive. Although investments into …

Alzheimer's disease (AD), the most common neurodegenerative disease, remains unclear in
terms of its underlying causative genes and effective therapeutic approaches. Meanwhile …

Background: Cellular senescence is a novel hallmark of cancer associated with patient
outcomes and tumor immunotherapy. However, the value of cellular senescence-related …

Objective This study aimed to investigate the impact of esketamine on the intestinal flora and
microenvironment in mice using mRNA transcriptome sequencing and 16S rRNA …

Basement membranes (BMs) are specialised extracellular matrices that maintain cellular
integrity and resist the breaching of carcinoma cells for metastases while regulating tumour …

Background Schizophrenia (SCZ) is a prevalent and serious mental disorder, and the exact
pathophysiology of this condition is not fully understood. In previous studies, it has been …

Metformin is widely used in the treatment of type 2 diabetes (T2D) and plays a role in
antitumor and antiobesity processes. A recent study identified its direct molecular target …

Introduction Alzheimer's disease (AD) is a progressive and debilitating neurodegenerative
disorder prevalent among older adults. Although AD symptoms can be managed through …