The epidemiology and genetics of hyperuricemia and gout across major racial groups: a literature review and population genetics secondary database analysis

F Butler, A Alghubayshi, Y Roman - Journal of personalized medicine, 2021 - mdpi.com
Gout is an inflammatory condition caused by elevated serum urate (SU), a condition known
as hyperuricemia (HU). Genetic variations, including single nucleotide polymorphisms …

Health disparities of cardiometabolic disorders among Filipino Americans: implications for health equity and community-based genetic research

G Coronado, J Chio-Lauri, RD Cruz… - Journal of racial and …, 2021 - Springer
Health disparities are well-documented among different racial and ethnic minority groups in
the United States. Filipino Americans (FAs) are the third-largest Asian-American group in the …

Moving the needle in gout management: the role of culture, diet, genetics, and personalized patient care practices

YM Roman - Nutrients, 2022 - mdpi.com
Gout is a metabolic disorder, and one of the most common inflammatory arthritic conditions,
caused by elevated serum urate (SU). Gout is globally rising, partly due to global dietary …

[HTML][HTML] The Daniel K. Inouye College of Pharmacy Scripts: perspectives on the epidemiology of gout and hyperuricemia

YM Roman - Hawai'i Journal of Medicine & Public Health, 2019 - ncbi.nlm.nih.gov
Gout is the most common inflammatory arthritic condition affecting more men than women.
Hyperuricemia and the deposition of urate crystals into the joints are the hallmarks of gout …

Genetic assessment of hyperuricemia and gout in Asian, Native Hawaiian, and Pacific Islander subgroups of pregnant women: biospecimens repository cross …

A Alghubayshi, A Edelman, K Alrajeh, Y Roman - BMC rheumatology, 2022 - Springer
Background Gout, an inflammatory condition, is characterized by the precipitation of
monosodium urate crystals (MSU) in or around distal joints. The latter is caused by chronic …

The frequency of rs2231142 in ABCG2 among Asian subgroups: implications for personalized rosuvastatin dosing

K Alrajeh, YM Roman - Pharmacogenomics, 2023 - Taylor & Francis
Statins are widely used medications for the primary and secondary prevention of
cardiovascular diseases. Statin-induced musculoskeletal symptoms are the primary adverse …

The prevalence of the gout-associated polymorphism rs2231142 G>T in ABCG2 in a pregnant female Filipino cohort

Y Roman, M Tiirikainen, E Prom-Wormley - Clinical rheumatology, 2020 - Springer
Gout is a metabolic disorder and one of the most common arthritic conditions. Hyperuricemia
is the hallmark of developing gout and mostly caused by uric acid underexcretion. Gout …

Gout prevalence in the Hmong: a prime example of health disparity and the role of community-based genetic research

YM Roman, K Lor, T Xiong, K Culhane-Pera… - Personalized …, 2021 - Taylor & Francis
Individuals of distinct Asian backgrounds are commonly aggregated as Asian, which could
mask the differences in the etiology and prevalence of health conditions in the different …

Engaging Hmong adults in genomic and pharmacogenomic research: Toward reducing health disparities in genomic knowledge using a community-based …

KA Culhane-Pera, RJ Straka, MK Moua… - Journal of community …, 2017 - Springer
Advancing precision medicine relies in part on examining populations that may exhibit
unique genetic variants that impact clinical outcomes. Failure to include diverse populations …

[HTML][HTML] Cardiometabolic genomics and pharmacogenomics investigations in Filipino Americans: steps towards precision health and reducing health disparities

YM Roman, D McClish, ET Price, RT Sabo… - American heart journal …, 2022 - Elsevier
Abstract Background Filipino Americans (FAs) are the third-largest Asian American
subgroup in the United States (US). Some studies showed that FAs experience more …