[HTML][HTML] Bioactive compounds of citrus fruits: A review of composition and health benefits of carotenoids, flavonoids, limonoids, and terpenes

RK Saini, A Ranjit, K Sharma, P Prasad, X Shang… - Antioxidants, 2022 - mdpi.com
The increased consumption of fruits, vegetables, and whole grains contributes to the
reduced risk of many diseases related to metabolic syndrome, including neurodegenerative …

[HTML][HTML] The Second Life of Citrus Fruit Waste: A Valuable Source of Bioactive Compounds

C Russo, A Maugeri, GE Lombardo, L Musumeci… - Molecules, 2021 - mdpi.com
Citrus fruits (CF) are among the most widely cultivated fruit crops throughout the world and
their production is constantly increasing along with consumers' demand. Therefore, huge …

[HTML][HTML] Targets involved in the anti-cancer activity of quercetin in breast, colorectal and liver neoplasms

A Maugeri, A Calderaro, GT Patanè, M Navarra… - International Journal of …, 2023 - mdpi.com
Phytochemicals have long been effective partners in the fight against several diseases,
including cancer. Among these, flavonoids are valuable allies for both cancer prevention …

[HTML][HTML] Molecular pathways involved in the anti-cancer activity of flavonols: a focus on myricetin and kaempferol

MR Felice, A Maugeri, G De Sarro, M Navarra… - International Journal of …, 2022 - mdpi.com
Natural compounds have always represented valuable allies in the battle against several
illnesses, particularly cancer. In this field, flavonoids are known to modulate a wide panel of …

[HTML][HTML] Oleacein attenuates lipopolysaccharide-induced inflammation in THP-1-derived macrophages by the inhibition of TLR4/MyD88/NF-κB pathway

S Cirmi, A Maugeri, C Russo, L Musumeci… - International Journal of …, 2022 - mdpi.com
It is known that plant phenolic compounds exert anti-inflammatory activity through both anti-
oxidant effects and modulation of pivotal pro-inflammatory factors. Recently, Olea europaea …

[HTML][HTML] Inflammation and Obesity: The Pharmacological Role of Flavonoids in the Zebrafish Model

C Russo, A Maugeri, L Musumeci, G De Sarro… - International journal of …, 2023 - mdpi.com
A Mediterranean-style diet is highly encouraged thanks to its healthy food pattern, which
includes valuable nutraceuticals such as polyphenols. Among these, flavonoids are …

[HTML][HTML] The Anticancer Effect of a Flavonoid-Rich Extract of Bergamot Juice in THP-1 Cells Engages the SIRT2/AKT/p53 Pathway

A Maugeri, C Russo, L Musumeci, GE Lombardo… - Pharmaceutics, 2022 - mdpi.com
Novel targets are constantly sought to fight hematologic malignancies. In this regard, high
levels of SIRT2 expression are associated with unfavorable prognosis of acute myeloid …

[HTML][HTML] Mediterranean diet as a shield against male infertility and cancer risk induced by environmental pollutants: a focus on flavonoids

L Montano, A Maugeri, MG Volpe, S Micali… - International Journal of …, 2022 - mdpi.com
The role of environmental factors in influencing health status is well documented. Heavy
metals, polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls, dioxins …

[HTML][HTML] The SIRT2 pathway is involved in the antiproliferative effect of flavanones in human leukemia monocytic THP-1 cells

C Russo, A Maugeri, L De Luca, R Gitto, GE Lombardo… - Biomedicines, 2022 - mdpi.com
Acute myeloid leukemia (AML) represents the most alarming hematological disease for
adults. Several genetic modifications are known to be pivotal in AML; however, SIRT2 over …

[HTML][HTML] Bergamottin and 5-Geranyloxy-7-methoxycoumarin Cooperate in the Cytotoxic Effect of Citrus bergamia (Bergamot) Essential Oil in Human Neuroblastoma …

A Maugeri, GE Lombardo, L Musumeci, C Russo… - Toxins, 2021 - mdpi.com
The plant kingdom has always been a treasure trove for valuable bioactive compounds, and
Citrus fruits stand out among the others. Bergamottin (BRG) and 5-geranyloxy-7 …