Impact of concomitant medications on the efficacy of immune checkpoint inhibitors: an umbrella review
H Li, L Zhang, F Yang, R Zhao, X Li, H Li - Frontiers in Immunology, 2023 - frontiersin.org
Introduction Cancer is a major global health concern, and immune checkpoint inhibitors
(ICIs) offer a promising treatment option for cancer patients. However, the efficacy of ICIs can …
(ICIs) offer a promising treatment option for cancer patients. However, the efficacy of ICIs can …
Immune Checkpoint Inhibitors and the Exposome: Host-Extrinsic Factors Determine Response, Survival, and Toxicity
EG Pizzutilo, R Romanò, L Roazzi, AG Agostara… - Cancer Research, 2023 - AACR
Cancer immunotherapy, largely represented by immune checkpoint inhibitors (ICI), has led
to substantial changes in preclinical cancer research and clinical oncology practice over the …
to substantial changes in preclinical cancer research and clinical oncology practice over the …
PD-L1/PD-1 pathway: a potential neuroimmune target for pain relief
D Deng, T Zhang, L Ma, W Zhao, S Huang, K Wang… - Cell & Bioscience, 2024 - Springer
Pain is a common symptom of many diseases with a high incidence rate. Clinically, drug
treatment, as the main method to relieve pain at present, is often accompanied by different …
treatment, as the main method to relieve pain at present, is often accompanied by different …
[HTML][HTML] Mu opioid receptor mRNA overexpression predicts poor prognosis among 18 common solid cancers: A pan-cancer analysis
W Sun, S Zhuang, M Cheng, Z Qiu - Frontiers in Oncology, 2023 - frontiersin.org
Background: Opioids are widely used for patients with solid tumors during surgery and for
cancer pain relief. We conducted a pan-cancer genomic analysis to investigate the …
cancer pain relief. We conducted a pan-cancer genomic analysis to investigate the …
A novel investigation into the negative impact of opioid use on the efficacy of immune checkpoint inhibitors in advanced non-small cell lung cancer patients
H Guo, Y Li, J Lin, D Li, J Yang, J Wang, J Mao… - International …, 2024 - Elsevier
Abstract Objective Immune checkpoint inhibitors (ICIs) have effectively improved the clinical
outcome of advanced non-small cell lung cancer (NSCLC). Opioids are commonly used for …
outcome of advanced non-small cell lung cancer (NSCLC). Opioids are commonly used for …
Clinical implications of the Drug-Drug interaction in cancer patients treated with innovative oncological treatments
F Santamaria, M Roberto, D Buccilli… - Critical Reviews in …, 2024 - Elsevier
In the last two-decades, innovative drugs have revolutionized cancer treatments,
demonstrating a significant improvement in overall survival. These drugs may present …
demonstrating a significant improvement in overall survival. These drugs may present …
[HTML][HTML] Opioids and immune checkpoint inhibitors differentially regulate a common immune network in triple-negative breast cancer
JR Scarpa, G Montagna, G Plitas, A Gulati… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Background Opioids are the primary analgesics for cancer pain. Recent clinical evidence
suggests opioids may counteract the effect of immune checkpoint inhibition (ICI) …
suggests opioids may counteract the effect of immune checkpoint inhibition (ICI) …