Oxidative stress has been linked with a variety of diseases, being involved in the debut
and/or progress of several neurodegenerative disorders. This review intends to summarize …

The prevalence of cerebrovascular disease increases with age, placing the elderly at a
greater lifetime risk for dementia. Vascular cognitive impairment (VCI) encompasses a …

Abstract Peroxynitrite (ONOO−), one of the reactive oxygen and nitrogen species (RONS), is
famous for its potent oxidation and nitration capabilities and plays crucial roles in various …

Transient or permanent loss of tissue perfusion due to ischaemic stroke can lead to damage
to the neurovasculature, and disrupt brain homeostasis, causing long-term motor and …

Cancer with a complex pathological process is a major disease to human welfare. Due to
the imbalance between oxygen (O2) supply and consumption, hypoxia is a natural …

Brain cancer is regarded among the deadliest forms of cancer worldwide. The distinct tumor
microenvironment and inherent characteristics of brain tumor cells virtually render them …

Reactive oxygen species (ROS) is a term encompassing a group of highly reactive oxygen-
derived molecules. In physiological systems, ROS production exists in concert with …

The concept of central nervous system (CNS) inflammation has evolved over the last
decades. Neuroinflammation is the response of reactive CNS components to altered …

Alzheimer's disease (AD) is a neurodegenerative disease with amyloid beta (Aβ) deposition
and intracellular neurofibrillary tangles (NFTs) as its characteristic pathological changes …

Simple Summary The term hypoxia is used to describe biological situations where
insufficient levels of oxygen exist. Hypoxia and hypoxic states can occur in a range of …