Beyond safety: mapping the ethical debate on heritable genome editing interventions

M Almeida, R Ranisch - Humanities and Social Sciences …, 2022 - nature.com
Genetic engineering has provided humans the ability to transform organisms by direct
manipulation of genomes within a broad range of applications including agriculture (eg, GM …

Setting ethical limits on human gene editing after the fall of the somatic/germline barrier

JH Evans - Proceedings of the National Academy of …, 2021 - National Acad Sciences
The ethical debate about what is now called human gene editing (HGE) has gone on for
more than 50 y. For nearly that entire time, there has been consensus that a moral divide …

Human germline and heritable genome editing: the global policy landscape

F Baylis, M Darnovsky, K Hasson, TM Krahn - The CRISPR Journal, 2020 - liebertpub.com
Discussions and debates about the governance of human germline and heritable genome
editing should be informed by a clear and accurate understanding of the global policy …

Coverage of allies, allyship and disabled people: A scoping review

G Wolbring, A Lillywhite - Societies, 2023 - mdpi.com
Disabled people face many problems in their lived reality, as evidenced by the content of the
UN Convention on the Rights of Persons with Disabilities. Disabled people are constantly …

Heritable genome editing: ethical aspects of a developing domain

S Segers - Human Reproduction, 2023 - academic.oup.com
In the past decade, scientific developments in human germline genome editing (GGE) have
reinvigorated questions about research ethics, responsible innovation, and what it means to …

Initial heritable genome editing: mapping a responsible pathway from basic research to the clinic

R Ranisch, K Trettenbach, G Arnason - Medicine, Health Care and …, 2023 - Springer
Abstract Following the Second Summit on Human Gene Editing in Hong Kong in 2018,
where the birth of two girls with germline genome editing was revealed, the need for a …

Changes in opinions about human germline gene editing as a result of the Dutch DNA-dialogue project

D Houtman, B Vijlbrief, M Polak, J Pot… - European Journal of …, 2023 - nature.com
Abstract Public engagement for Human Germline Genome Editing (HGGE) has often been
called for, for example by the WHO. However, the impact of public engagement remains …

New insights into the therapeutic applications of CRISPR/Cas9 genome editing in breast cancer

M Ahmed, GH Daoud, A Mohamed, R Harati - Genes, 2021 - mdpi.com
Breast cancer is one of the most prevalent forms of cancer globally and is among the leading
causes of death in women. Its heterogenic nature is a result of the involvement of numerous …

The Promethean biohacker: on consumer biohacking as a labour of love

VM Lima, LA Pessoa, RW Belk - … and Biotechnologies in …, 2022 - taylorfrancis.com
Just as the mythical Greek Titan Prometheus created humans and brought them the
technology of fire, the biohackers studied here seek to recreate humanity and bring us …

Germline genome modification through novel political, ethical, and social lenses

V Xafis, GO Schaefer, MK Labude, Y Zhu, S Holm… - PLoS …, 2021 - journals.plos.org
Much has been written about gene modifying technologies (GMTs), with a particularly strong
focus on human germline genome editing (HGGE) sparked by its unprecedented clinical …