Purpose Radiotherapy (RT), as part of trimodal therapy, is an attractive alternative treatment
in patients with urothelial muscle-invasive bladder cancer (MIBC). There is accumulating …

Background: Advances in cancer medicines have resulted in tangible health impacts, but the
magnitude of benefits of approved cancer medicines could vary greatly. Health Technology …

Myeloid-derived suppressor cells (MDSCs) are one of the key players that contribute to
immune evasion. The purpose of the present study was to investigate whether MDSCs could …

Purpose Radiation therapy (RT) is mainly used for bladder preservation in patients with
muscle-invasive bladder cancer. The response of urothelial tumors to RT remains …

Patients with muscle-infiltrating bladder cancer (MIBC) present a high risk of postoperative
recurrence and death from metastatic urothelial cancer despite surgical resection. Before the …

Cancer immunotherapies, which rely on training or stimulating our immune system, are
revolutionizing the way of cancer treatment. In recent years, these revolutionary weapons …

Simple Summary There are a number of scientific questions that are novel or controversial,
which are clinically relevant in the real-world setting for patients diagnosed with bladder …

Monoclonal antibodies targeting the checkpoint inhibitors (CPIs), programmed cell death
protein-1 or programmed cell death ligand-1, are changing the landscape of urothelial …

Value of Biomarker Expression for Randomized Clinical Trial Design: One (More) Missed
Opportunity Value of Biomarker Expression for Randomized Clinical Trial Design: One (More) …