The infinite time of oral drug absorption was conceived from the first day of the birth of
pharmacokinetics when H. Dost introduced the term pharmacokinetics in his book published …

Purpose To develop physiologically based finite time pharmacokinetic (PBFTPK) models for
the analysis of oral pharmacokinetic data. Methods The models are based on the passive …

The Finite Absorption Time (FAT) concept en route to PBPK modeling and pharmacometrics
| Journal of Pharmacokinetics and Pharmacodynamics Skip to main content SpringerLink …

To date, mechanistic modeling of oral drug absorption has been achieved via the use of
physiologically based pharmacokinetic (PBPK) modeling, and more specifically …

This book casts new light on the field of oral drug absorption. It outlines both the concept of
the past and the novel concept of Finite Absorption Time (FAT). In addition, the authors …

Objective The first-order absorption is a common model used in Pharmacokinetics. The
absorption of some drugs follows carrier mediated transport. It has been proposed that the …

Purpose Το formulate a methodology for the assessment of bioequivalence using metrics,
which are based on the physiologically sound FAT concept. Methods The equations of the …

In this study, two intramammary infusions of cefquinome sulfate were investigated for
pharmacokinetics and bioavailability. Twelve lactating cows for each group were …

Objectives: Pharmacokinetics since its inception (1) in 1953 has been built on the notion of
an infinite time for oral drug absorption; in fact, this is like a dogma in contemporary …

The concept of finite absorption time is applied to a detailed discussion of generated models
in bioavailability and bioequivalence. Considering detailed expressions for full and partial …