Medical micro/nanorobots in precision medicine
Advances in medical robots promise to improve modern medicine and the quality of life.
Miniaturization of these robotic platforms has led to numerous applications that leverages …
Miniaturization of these robotic platforms has led to numerous applications that leverages …
3D extracellular matrix mimics: fundamental concepts and role of materials chemistry to influence stem cell fate
Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …
Dynamic covalent hydrogels as biomaterials to mimic the viscoelasticity of soft tissues
S Tang, BM Richardson, KS Anseth - Progress in Materials Science, 2021 - Elsevier
The extracellular matrix (ECM) and its mechanical properties play an important role in
regulating the cellular responses that occur during tissue regeneration, wound healing, and …
regulating the cellular responses that occur during tissue regeneration, wound healing, and …
Rolling circle amplification (RCA)-based DNA hydrogel
C Yao, R Zhang, J Tang, D Yang - Nature protocols, 2021 - nature.com
DNA hydrogels have unique properties, including sequence programmability, precise
molecular recognition, stimuli-responsiveness, biocompatibility and biodegradability, that …
molecular recognition, stimuli-responsiveness, biocompatibility and biodegradability, that …
Static and dynamic: evolving biomaterial mechanical properties to control cellular mechanotransduction
The extracellular matrix (ECM) is a highly dynamic system that constantly offers physical,
biological, and chemical signals to embraced cells. Increasing evidence suggests that …
biological, and chemical signals to embraced cells. Increasing evidence suggests that …
High-throughput methods in the discovery and study of biomaterials and materiobiology
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …
pivotal role in the development of novel implants, biomedical devices, and tissue …
Surface roughness gradients reveal topography‐specific mechanosensitive responses in human mesenchymal stem cells
Y Hou, W Xie, L Yu, LC Camacho, C Nie, M Zhang… - Small, 2020 - Wiley Online Library
The topographic features of an implant, which mechanically regulate cell behaviors and
functions, are critical for the clinical success in tissue regeneration. How cells sense and …
functions, are critical for the clinical success in tissue regeneration. How cells sense and …
[HTML][HTML] Advances in engineering human tissue models
CM Moysidou, C Barberio, RM Owens - Frontiers in bioengineering …, 2021 - frontiersin.org
Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate
the investigation and understanding of specific biological events and processes under …
the investigation and understanding of specific biological events and processes under …
Double rolling circle amplification generates physically cross-linked DNA network for stem cell fishing
C Yao, H Tang, W Wu, J Tang, W Guo… - Journal of the …, 2020 - ACS Publications
Stem cells have been widely studied in cell biology and utilized in cell-based therapies, and
fishing stem cells from marrow is highly challenging due to the ultralow content. Herein, a …
fishing stem cells from marrow is highly challenging due to the ultralow content. Herein, a …
Extended exposure to stiff microenvironments leads to persistent chromatin remodeling in human mesenchymal stem cells
Bone marrow derived human mesenchymal stem cells (hMSCs) are a promising cell source
for regenerative therapies; however, ex vivo expansion is often required to achieve clinically …
for regenerative therapies; however, ex vivo expansion is often required to achieve clinically …