The impact of respiratory virus infections on the health of children and adults can be very
significant. Yet, in contrast to most other childhood infections as well as other viral and …

Viruses are highly dependent on the host they infect. Their dependence triggers processes
of virus–host co-adaptation, enabling viruses to explore host resources whilst escaping …

The innate antiviral response is integral in protecting the host against virus infection. Many
proteins regulate these signaling pathways including ubiquitin enzymes. The ubiquitin …

Abstract Histone deacetylase 6 (HDAC6) is a class IIb histone deacetylase that contains two
catalytic domains and a zinc-finger ubiquitin binding domain (ZnF-UBP) domain. The …

Ubiquitination of proteins is a post-translational modification process with many different
cellular functions, including protein stability, immune signaling, antiviral functions and virus …

Influenza is a zoonotic respiratory disease of major public health interest due to its pandemic
potential, and a threat to animals and the human population. The influenza A virus genome …

Hepatitis C virus (HCV) and the malaria parasite Plasmodium use the membrane protein
CD81 to invade human liver cells. Here we mapped 33 host protein interactions of CD81 in …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative virus of the
pandemic coronavirus disease 2019 (COVID-19). Evaluating the immunological factors and …

Influenza viruses are respiratory pathogens that represent a significant threat to public
health, despite the large-scale implementation of vaccination programs. It is necessary to …

The ubiquitin system denotes a potent post-translational modification machinery that is
capable of activation or deactivation of target proteins through reversible linkage of a single …