[HTML][HTML] Climate change, airborne allergens, and three translational mitigation approaches

PJ Beggs, B Clot, M Sofiev, FH Johnston - EBioMedicine, 2023 - thelancet.com
One of the important adverse impacts of climate change on human health is increases in
allergic respiratory diseases such as allergic rhinitis and asthma. This impact is via the …

[HTML][HTML] Pollen allergens for molecular diagnosis

I Pablos, S Wildner, C Asam, M Wallner… - Current allergy and …, 2016 - Springer
Pollen allergens are one of the main causes of type I allergies affecting up to 30% of the
population in industrialized countries. Climatic changes affect the duration and intensity of …

Multiomics profiling of Alzheimer's disease serum for the identification of autoantibody biomarkers

P San Segundo-Acosta, A Montero-Calle… - Journal of Proteome …, 2021 - ACS Publications
New biomarkers of Alzheimer's disease (AD) with a diagnostic value in preclinical and
prodromal stages are urgently needed. AD-related serum autoantibodies are potential …

Recombinant allergens in structural biology, diagnosis, and immunotherapy

A Tscheppe, H Breiteneder - International archives of allergy and …, 2017 - karger.com
The years 1988-1995 witnessed the beginning of allergen cloning and the generation of
recombinant allergens, which opened up new avenues for the diagnosis and research of …

[HTML][HTML] Multiplexed monitoring of a novel autoantibody diagnostic signature of colorectal cancer using HaloTag technology-based electrochemical immunosensing …

M Garranzo-Asensio, A Guzmán-Aránguez… - Theranostics, 2020 - ncbi.nlm.nih.gov
Background and Purpose: The humoral immune response in cancer patients can be used
for early detection of the disease. Autoantibodies raised against tumor-associated antigens …

A hypoallergenic polygalacturonase isoform from olive pollen is implicated in pollen-pollen cross-reactivity

C Oeo-Santos, S Mas, J Quiralte, C Colás… - International archives of …, 2018 - karger.com
Background: Cross-reactivity reactions between allergenic polygalacturonases (PGs) from
different biological sources, especially foods and pollens from the Oleaceae family, have …

Aerobiological importance and allergic sensitization to Amaranthaceae under arid climate conditions

B Elvira-Rendueles, JJ Zapata, JC Miralles… - Science of the Total …, 2017 - Elsevier
Species of the Amaranthaceae family are abundant in the Southeast of Spain, one of the
driest areas in Europe. The Amaranthaceae include species of interest from the point of view …

A relevant IgE-reactive 28 kDa protein identified from Salsola kali pollen extract by proteomics is a natural degradation product of an integral 47 kDa polygalaturonase

S Mas, C Oeo-Santos, J Cuesta-Herranz… - … et Biophysica Acta (BBA …, 2017 - Elsevier
A highly prevalent IgE-binding protein band of 28 kDa is observed when Salsola kali pollen
extract is incubated with individual sera from Amaranthaceae pollen sensitized patients. By …

A recombinant isoform of the Ole e 7 olive pollen allergen assembled by de novo mass spectrometry retains the allergenic ability of the natural allergen

C Oeo-Santos, S Mas, S Benedé, M López-Lucendo… - Journal of …, 2018 - Elsevier
The allergenic non-specific lipid transfer protein Ole e 7 from olive pollen is a major allergen
associated with severe symptoms in areas with high olive pollen levels. Despite its clinical …

[HTML][HTML] Enhanced sensitivity of capture IgE‑ELISA based on a recombinant Der f 1/2 fusion protein for the detection of IgE antibodies targeting house dust mite …

Z Zhang, Z Cai, Y Hou, J Hu… - Molecular Medicine …, 2019 - spandidos-publications.com
The detection of allergen‑specific immunoglobulin (Ig) E is an important method for the
diagnosis of IgE‑mediated allergic diseases. The sensitivity of the indirect IgE‑ELISA method …