The recent identification of cannabinoid receptors and their endogenous lipid ligands has
triggered an exponential growth of studies exploring the endocannabinoid system and its …

Major depressive disorder (MDD) is one of the most prevalent and debilitating disorders.
Current available treatments are somehow limited, so alternative therapeutic approaches …

As far as can be ascertained from archeological sources, preparations of the hemp
Cannabis sativa L. were widely used by humans for either therapeutic or ritual purposes in …

The past decade has seen an expansion of research and knowledge on pharmacotherapy
for the treatment of alcohol dependence. The Food and Drug Administration (FDA)-approved …

Several disorders have been associated with mutations in Na, K-ATPase α isoforms (rapid-
onset dystonia parkinsonism, familial hemiplegic migraine type-2), as well as reduction in …

These experiments aimed to assess whether enhanced activity at the cannabinoid CB1
receptor elicits antidepressant-like effects. To examine this we administered 1 and 5 mg/kg …

Bipolar affective disorder is often poorly controlled by prescribed drugs. Cannabis use is
common in patients with this disorder and anecdotal reports suggest that some patients take …

The endocannabinoid system is a neuromodulatory system which is known to regulate
emotional, cognitive, neurovegetative and motivational processes. Substantial evidence has …

Background & Objective: Cannabis is one of the earliest cultivated plants. Cannabis of
industrial utility and culinary value is generally termed as hemp. Conversely, cannabis that is …

Cannabinoids are a structurally diverse group of mostly lipophilic molecules that bind to
cannabinoid receptors. In fact, endogenous cannabinoids (endocannabinoids) are a class of …