Mammalian zona pellucida glycoproteins: structure and function during fertilization

SK Gupta, B Bhandari, A Shrestha, BK Biswal… - Cell and tissue …, 2012 - Springer
Zona pellucida (ZP) is a glycoproteinaceous translucent matrix that surrounds the
mammalian oocyte and plays a critical role in the accomplishment of fertilization. In humans …

[HTML][HTML] Human zona pellucida glycoproteins: binding characteristics with human spermatozoa and induction of acrosome reaction

SK Gupta - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Human zona pellucida (ZP) matrix is composed of four glycoproteins designated as ZP
glycoprotein-1 (ZP1),-2 (ZP2),-3 (ZP3), and-4 (ZP4). Mutations in the genes encoding human …

Four zona pellucida glycoproteins are expressed in the human

L Lefièvre, SJ Conner, A Salpekar… - Human …, 2004 - academic.oup.com
BACKGROUND: The zona pellucida (ZP) is an extracellular glycoprotein matrix which
surrounds all mammalian oocytes. Recent data have shown the presence of four human …

The human egg's zona pellucida

SK Gupta - Current topics in developmental biology, 2018 - Elsevier
Human zona pellucida (ZP) matrix, a delicate network of thin interconnected filaments, is
primarily composed of four glycoproteins, namely, ZP1, ZP2, ZP3, and ZP4. All four zona …

Structure and function of the proteins of the mammalian zona pellucida

SV Prasad, SM Skinner, C Carino, N Wang… - Cells Tissues …, 2000 - karger.com
The zona pellucida (ZP) is the extracellular matrix that plays important roles in sperm-egg
interaction. The ZP is composed of three major glycoproteins that exhibit heterogeneity due …

Identification of the true human orthologue of the mouse Zp1 gene: evidence for greater complexity in the mammalian zona pellucida?

DC Hughes, CLR Barratt - Biochimica Et Biophysica Acta (BBA)-Gene …, 1999 - Elsevier
The mammalian zona pellucida is a mixture of glycoproteins, believed to be encoded by
three distinct genes, ZP1/ZPB, ZP2/ZPA, and ZP3/ZPC. We have now determined that the …

Relevance of glycosylation of human zona pellucida glycoproteins for their binding to capacitated human spermatozoa and subsequent induction of acrosomal …

S Chakravarty, S Kadunganattil… - Molecular …, 2008 - Wiley Online Library
To delineate the functional aspects of zona pellucida (ZP) glycoproteins during fertilization in
human, in the present study, fluorochrome‐conjugated Escherichia coli (E. coli)‐and …

Characterization of human zona pellucida glycoproteins

AR Bauskin, DR Franken… - Molecular human …, 1999 - academic.oup.com
The human egg may only be fertilized by one spermatozoon to prevent polyploidy. In most
mammals, the primary block to polyspermy occurs at the zona pellucida (ZP). Little is known …

Native human zona pellucida glycoproteins: purification and binding properties

PCN Chiu, BST Wong, CL Lee, RTK Pang… - Human …, 2008 - academic.oup.com
BACKGROUND Fertilization starts with the binding of the spermatozoa to the zona pellucida
(ZP) of the oocyte. Such binding is a carbohydrate-mediated event and consists of a series …

Expression and purification of recombinant human zona pellucida proteins

JD Harris, CA Seid, GK Fontenot, HF Liu - Protein expression and …, 1999 - Elsevier
Recombinant human zona pellucida (rhZP) proteins (minus the N-terminal leader and the C-
terminal transmembrane-like domain) were expressed in four different expression systems …