Immunomodulatory properties of mesenchymal stem cells: A potential therapeutic strategy for allergic rhinitis

M Wang, N Zhao, C Wang, ZB Jin, L Zhang - Allergy, 2023 - Wiley Online Library
Allergic rhinitis is a highly prevalent chronic inflammatory disorder of the nasal mucosa that
poses a significant burden on patients' health and quality of life. Current therapies for …

Respiratory comorbidities in severe asthma: focus on the pediatric age

A Licari, B Andrenacci, ME Di Cicco… - Expert Review of …, 2023 - Taylor & Francis
Introduction Asthma comorbidities are a frequent cause of adverse outcomes, such as poor
asthma control, frequent asthma attacks, reduced quality of life, and higher healthcare costs …

[HTML][HTML] Oxidative stress and antioxidants in chronic rhinosinusitis with nasal polyps

J Tai, JM Shin, J Park, M Han, TH Kim - Antioxidants, 2023 - mdpi.com
Oxidative stress results from an imbalance between the production of reactive oxygen
species and the body's antioxidant defense system. It plays an important role in the …

[HTML][HTML] Identification of Hit Compounds Using Artificial Intelligence for the Management of Allergic Diseases

J Byun, J Tai, B Kim, J Kim, S Jung, J Lee… - International journal of …, 2024 - mdpi.com
This study aimed to identify and evaluate drug candidates targeting the kinase inhibitory
region of suppressor of cytokine signaling (SOCS) 3 for the treatment of allergic rhinitis (AR) …

ATP functions as a primary alarmin in allergen-induced type 2 immunity

SM O'Grady, H Kita - American Journal of Physiology-Cell …, 2023 - journals.physiology.org
Environmental allergens that interact with the airway epithelium can activate cellular stress
pathways that lead to the release of danger signals known as alarmins. The mechanisms of …

[HTML][HTML] The Primary Prevention of Atopy: Does Early Exposure to Cats and Dogs Prevent the Development of Allergy and Asthma in Children? A Comprehensive …

C Indolfi, E D'Addio, CL Bencivenga, G Rivetti, I Bettini… - Life, 2023 - mdpi.com
The current literature shows mixed results relating to the significance of environmental
exposure, such as owning a pet, and the development of atopy in children. Our review …

Maximal medical treatment of adenoid hypertrophy: a prospective study of preschool children

A Zwierz, K Domagalski, K Masna, P Burduk - European Archives of Oto …, 2024 - Springer
Purpose This study aimed to examine the effectiveness of the combined maximal medical
treatment for adenoid hypertrophy in preschool children. Methods Sixty-four children …

[HTML][HTML] Effects of Nasal Solution Incorporating Resveratrol and Carboxymethyl-Β-Glucan in Preschool Non-Atopic Children with Wheezing

C Indolfi, C Mignini, F Valitutti, I Bizzarri, G Dinardo… - Nutrients, 2024 - mdpi.com
Upper respiratory tract infections (URTI) account for more than 80% of wheezing episodes in
children with a high incidence of hospitalization in preschool age. Most children with …

Comparing available treatments for pollen-induced allergic rhinitis in children

A Klain, C Indolfi, G Dinardo, F Decimo… - Expert Review of …, 2022 - Taylor & Francis
Introduction Pollen-induced allergic rhinitis (PIAR) is a widespread disease in children, and
its prevalence is rapidly evolving. In addition, it may be associated with other atopic …

Study protocol: the biologics in severe chronic rhinosinusitis with nasal polyps survey

V Favier, C Daveau, F Carsuzaa, M Fieux… - BMJ open, 2024 - bmjopen.bmj.com
Introduction Chronic rhinosinusitis with nasal polyps (CRSwNP) is a frequent condition
affecting approximately 2% of the population. Medical treatment consists long-term use of …