Despite an extensive body of reported information about peripheral and central mechanisms
involved in the pathophysiology of IBS symptoms, no comprehensive disease model has …

Background In 2013, a systematic review and Delphi consensus reported that specific
probiotics can benefit adult patients with irritable bowel syndrome (IBS) and other …

Functional bowel disorders (FBD), mainly irritable bowel syndrome (IBS) and functional
constipation (FC, also called chronic idiopathic constipation), are very common worldwide …

Imaging of the living human brain is a powerful tool to probe the interactions between brain,
gut and microbiome in health and in disorders of brain–gut interactions, in particular IBS …

Visceral pain is a global term used to describe pain originating from the internal organs,
which is distinct from somatic pain. It is a hallmark of functional gastrointestinal disorders …

Introduction: Parkinson's disease (PD) affects the nerves of the entire gastrointestinal (GI)
tract and may result in profound gastrointestinal (GI) dysfunction leading to poor patient …

Eluxadoline (Viberzi™), developed by Actavis (now Allergan), is an orally administered, first-
in-class compound that functions as both a µ-opioid receptor agonist and a δ-opioid receptor …

The study evaluated the efficacy of ID-JPL934, a probiotic preparation containing
Lactobacillus johnsonii IDCC 9203, Lactobacillus plantarum IDCC 3501 and …

Background Diarrhea-predominant irritable bowel syndrome (IBS-D) is a common chronic
digestive disease. Recent observational studies have reported that the Chinese herbal …

Background Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder
characterized by abdominal pain and change of bowel habit without organic disease. A …