The burden of heart failure (HF), developing after myocardial infarction MI, still represents a
major issue in clinical practice. Failure of appropriate resolution of inflammation during post …

Vascular diseases are the main cause of morbidity and mortality. The vascular extracellular
matrix (ECM) is essential in mechanical support, also regulating the cellular behavior …

Myocardial infarction (MI) is defined as evidence of myocardial necrosis consistent with
prolonged ischemia. In response to MI, the myocardium undergoes a series of wound …

Arterial hypertension is the most important risk factor for the development of cardiovascular
disease. Recently, aircraft noise has been shown to be associated with elevated blood …

Amyotrophic lateral sclerosis (ALS) is a fatal disease of motor neurons that mainly affects the
motor cortex, brainstem, and spinal cord. Under disease conditions, microglia could possess …

Despite the importance of rapid adaptive responses in the course of inflammation and the
notion that post-transcriptional regulation plays an important role herein, relevant …

Aims Patients with chronic kidney disease (CKD) have an increased risk of cardiovascular
events and exhibit myocardial changes including left ventricular (LV) hypertrophy and …

MMP-12 is a metalloproteinase (MMP) mainly secreted by macrophages and regulating the
degradation of the extracellular matrix. MMP-12 is related to several diseases such as …

Cerebral cavernous malformations (CCMs) are dilated capillaries causing epilepsy and
stroke. Inheritance of a heterozygous mutation in CCM3/PDCD10 is responsible for the most …

Chagas disease (CD), caused by Trypanosoma cruzi, is a degenerative heart condition. In
the present study, we investigated the role of poly [ADP-ribose] polymerase 1/activator …