This review provides a detailed look at the attributes and immunologic mechanisms of
plasmid DNA vaccines and their utility as laboratory tools as well as potential human …

Protein toxins confer a defense against predation/grazing or a superior pathogenic
competence upon the producing organism. Such toxins have been perfected through …

DNA vaccines are a rapidly deployed next generation vaccination platform for treatment of
human and animal disease. DNA delivery devices, such as electroporation and needle free …

The food-grade bacterium Lactococcus lactis has been extensively investigated during the
last two decades as a delivery vector for therapeutic proteins, DNA and vaccine antigens …

The incidence of allergic diseases has increased to such a point that they have become
common and have reached epidemic levels. However, their pathogenesis is not fully …

Suppressor of cytokine signalling (SOCS) proteins bind to certain cytokine receptors, Janus
kinases and signalling molecules to regulate signalling pathways, thus controlling immune …

The design of nanomaterial-based nucleic acid formulations is one of the biggest
endeavours in the search for clinically applicable gene delivery systems. Biopolymers …

The IL‐1R/TLR family has been receiving considerable attention as potential regulators of
inflammation through their ability to act as either activators or suppressors of inflammation …

Airway diseases such as allergic asthma and rhinitis are characterized by a T-helper type 2
(Th2) response. Treatment of allergic airway diseases is currently limited to drugs that …

Objective This systematic review of randomized controlled trials (RCTs) aimed to evaluate
the efficacy and safety of moxibustion as a complementary or alternative treatment for …