Alzheimer's disease (AD) is the most common cause of dementia, affecting 35 million people
worldwide. One pathological feature of progressing AD is the loss of synapses. This is the …

The unprecedented rise in life expectancy observed in the last decades is leading to a
global increase in the ageing population, and age-associated diseases became an …

Abstract Chitinase‐3‐like protein 1 (CHI3L1/YKL‐40) has long been known as a biomarker
for early detection of neuroinflammation and disease diagnosis of Alzheimer's disease (AD) …

Alzheimer's disease (AD) is the most common neurodegenerative disease caused by
eventually aggregated amyloid β (Aβ) plaques in degenerating neurons of the aging brain …

Advances in the development of three-dimensional (3D) brain organoids maintained in vitro
have provided excellent opportunities to study brain development and neurodegenerative …

Alzheimer's disease (AD) is the most common form of dementia. Despite many years of
intense research, there is currently still no effective treatment. Multiple cell types contribute to …

Genetic and molecular mechanisms that play a causal role in mental illnesses are
challenging to elucidate, particularly as there is a lack of relevant in vitro and in vivo models …

Biomedical research on Alzheimer's disease (AD), breast cancer (BC) and prostate cancer
(PC) has globally improved our understanding of the etiopathological mechanisms …

Alzheimer's disease (AD) is the primary cause of dementia, to date. The urgent need to
understand the biological and biochemical processes related to this condition, as well as the …

In situ physiological signals of in vitro neural disease models are essential for studying
pathogenesis and drug screening. Currently, an increasing number of in vitro neural disease …