An updated World Health Organization (WHO) classification of female genital tumours was
published in autumn 2020. We discuss the major new additions to and changes from the …

Summary Background Human papillomavirus (HPV) DNA and p16 INK4a positivity have
crucial roles in the pathogenesis of vulvar cancer and vulvar intraepithelial neoplasia. We …

In der WHO-Klassifikation 2020 steht die Unterscheidung von HPV-assoziierten und HPV-
unabhängigen Plattenepithelkarzinomen des unteren weiblichen Genitales im Vordergrund …

Objective The aim of the study was to describe the features required for diagnosis of
differentiated vulvar intraepithelial neoplasia (dVIN) and vulvar aberrant maturation (VAM) …

Vulvar squamous cell carcinomas and their precursors are currently classified by the World
Health Organization based on their association with high-risk human papillomavirus (HPV) …

The risk of vulvar squamous cell carcinoma (VSCC) in patients with high‐grade vulvar
intraepithelial neoplasia (VIN) is considered lower in high‐grade squamous intraepithelial …

Human papillomavirus (HPV)-independent vulvar squamous cell carcinoma (VSCC) is an
aggressive clinical entity. Current diagnostic guidelines for premalignant lesions are …

Introduction Based on their etiological relationship with human papillomavirus (HPV), the
2020 WHO classification has divided vulvar squamous cell carcinomas (VSCC) into two …

Simple Summary Human papillomavirus (HPV) infection is a sexually transmitted disease
with high prevalence worldwide. Although most HPV infections do not lead to cancer, some …

Gynecologic malignancies, mainly including ovarian cancer, cervical cancer and
endometrial cancer, are leading causes of death among women worldwide with high …